3D (Three-dimensional) bioprinting double-nozzle device
A bioprinting and dual-nozzle technology, applied in the field of tissue engineering, can solve the problems of printing a single biological material and a single nozzle, and achieve the effect of improving survival rate and wide application range
Inactive Publication Date: 2018-06-12
YANGZHOU UNIV
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Problems solved by technology
[0004] The technical problem solved by the present invention is to provide a 3D bioprinting dual nozzle device to solve the problem that the existing printing device can only print a single biological material with a single nozzle
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Embodiment Construction
[0015] In order to illustrate the technical scheme and technical purpose of the present invention, the present invention will be further introduced below in conjunction with the accompanying drawings and specific embodiments.
[0016] combine figure 1 , a 3D bioprinting double nozzle device of the present invention, comprising a rotating motor 1, a connecting shaft 2, a linear drive mechanism, a nozzle 5, and a fixing seat 8;
[0017] The upper end of the fixed seat 8 is connected with the rotating shaft of the rotating motor 1 through the connecting shaft 2; the two sides of the fixed seat 8 are symmetrically provided with a linear drive mechanism; Mechanism: the linear drive mechanism can drive the spray head 5 to slide horizontally and linearly on the fixed seat 8 .
[0018] In some embodiments, the linear drive mechanism includes a drive motor 4 and a ball screw; the drive shaft of the drive motor 4 is connected to the ball screw. The ball screw is arranged on the fixed ...
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The invention discloses a 3D (Three-dimensional) bioprinting double-nozzle device, which comprises a rotating motor, a connecting shaft, linear driving mechanisms, nozzles and a permanent seat, wherein the upper end of the permanent seat is connected with the rotating shaft of the rotating motor through the connecting shaft; two sides of the permanent seat are symmetrically provided with the linear driving mechanisms; the two nozzles are symmetrically arranged on the linear driving mechanisms on two sides; the linear driving mechanisms can drive the nozzles to carry out horizontal linear sliding on the permanent seat. According to the 3D bioprinting double-nozzle device disclosed by the invention, single-nozzle and double-nozzle printing both can be realized; the switching frequency of thenozzles can be reduced to improve the printing efficiency; the one-time forming printing of two biomass composite materials can be realized, the survival rate of cells after printing can be improved,and the 3D bioprinting double-nozzle device is suitable for various biomass materials and has a wide range of use.
Description
technical field [0001] The invention belongs to the field of tissue engineering, in particular to a 3D bioprinting double nozzle device. Background technique [0002] For the treatment of damaged large soft tissues and internal organs, the transplantation of human tissues and organs is an extremely effective treatment method. However, due to the shortage of organ donor sources, immune rejection and other problems, there are insurmountable difficulties in the practical application of organ transplantation. Bio-3D printing technology uses computer-aided design to build three-dimensional scaffolds of cells, cell substrates and other biomass materials through layer-by-layer superposition methods, which have a certain porosity and generate living human organ tissues with certain functions. [0003] The current 3D bioprinting method in the construction of 3D tissue engineering is still relatively single, and can only print a single biomaterial. In the process of continuous develo...
Claims
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IPC IPC(8): C12M3/00C12M1/00
CPCC12M33/00
Inventor 张琦陈冬冬周骥平姜娅妮吴鹏鹏梁国栋
Owner YANGZHOU UNIV