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American cockroach oral ulcer film patch and preparation method thereof

A technology of American cockroach and oral ulcers, applied in the field of biomedicine, can solve the problems of affecting diet, speech, low utilization rate of drugs, large bitterness and astringency of drugs, etc., and achieves inhibiting the growth of pathogenic bacteria, promoting ulcer healing, and good curative effect. Effect

Inactive Publication Date: 2018-07-20
云南宁康生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Oral ulcers are often accompanied by a burning sensation. In severe cases, it will affect eating and speaking, and easily cause mood swings, which will affect the quality of life.
There are many shortcomings in the treatment of oral ulcers with conventional oral medicines, such as wide action sites, large dosage, low utilization rate of medicines, and bitter taste of medicines, etc.

Method used

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  • American cockroach oral ulcer film patch and preparation method thereof
  • American cockroach oral ulcer film patch and preparation method thereof
  • American cockroach oral ulcer film patch and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] 1) Prepare raw materials according to the following mass fractions:

[0050] American cockroach extract 1%,

[0051] Watermelon Frost 0.5%,

[0052] Calcined gypsum 0.2%,

[0053] Clove Extract 0.3%,

[0054] Polyvinyl alcohol 17-88 3.5%,

[0055] Sodium Carboxymethyl Cellulose 0.5%,

[0056] PEG-40 hydrogenated castor oil 0.4%,

[0057] Glycerin 1.5%,

[0058] The balance is water,

[0059] The sum of the above components is 100%;

[0060] 2) Take polyvinyl alcohol 17-88 and sodium carboxymethyl cellulose and mix evenly, then add water to mix evenly, and let it swell for 5 hours to obtain a mixture;

[0061] 3) Add Periplaneta americana extract, clove extract, watermelon cream, calcined gypsum, PEG-40 hydrogenated castor oil, and glycerin to the mixture in step 2) and mix well;

[0062] 4) Let the mixture in step 3) stand at 50°C until the defoaming is complete, spread it on a glass plate coated with liquid paraffin, dry it naturally, open the film, cut it int...

Embodiment 2

[0072] 1) Prepare raw materials according to the following mass fractions:

[0073] American cockroach extract 0.5%,

[0074] Watermelon Frost 0.9%,

[0075] Calcined gypsum 1.0%,

[0076] Clove Extract 1%,

[0077] Polyvinyl alcohol 17-88 5%,

[0078] Sodium Carboxymethyl Cellulose 1%,

[0079] PEG-40 hydrogenated castor oil 0.4%,

[0080] Glycerin 5%,

[0081] The balance is water,

[0082] The sum of the above components is 100%;

[0083] 2) Take polyvinyl alcohol 17-88 and sodium carboxymethyl cellulose and mix evenly, then add water to mix evenly, and let it swell for 4-8 hours to obtain a mixture;

[0084] 3) Add Periplaneta americana extract, clove extract, watermelon cream, calcined gypsum, PEG-40 hydrogenated castor oil, and glycerin to the mixture in step 2) and mix well;

[0085] 4) Put the mixture in step 3) at 40°C until the defoaming is complete, spread it on a glass plate coated with liquid paraffin, let it dry naturally, open the film, cut it into smal...

Embodiment 3

[0095] 1) Prepare raw materials according to the following mass fractions:

[0096] American cockroach extract 2.5%,

[0097] Watermelon Frost 1.1%,

[0098] Calcined gypsum 1.2%,

[0099] Clove Extract 0.1%,

[0100] Polyvinyl alcohol 17-88 2.5%,

[0101] Sodium Carboxymethyl Cellulose 1.5%,

[0102] PEG-40 hydrogenated castor oil 0.4%,

[0103] Glycerin 1.5%,

[0104] The balance is water,

[0105] The sum of the above components is 100%;

[0106] 2) Take polyvinyl alcohol 17-88 and sodium carboxymethyl cellulose and mix evenly, then add water to mix evenly, and let it swell for 4-8 hours to obtain a mixture;

[0107] 3) Add Periplaneta americana extract, clove extract, watermelon cream, calcined gypsum, PEG-40 hydrogenated castor oil, and glycerin to the mixture in step 2) and mix well;

[0108] 4) Let the mixture in step 3) stand at 70°C until the defoaming is complete, spread it on a glass plate coated with liquid paraffin, let it dry naturally, open the film, cu...

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Abstract

The invention discloses an American cockroach oral ulcer film patch and a preparation method thereof. The American cockroach oral ulcer film patch is prepared from the following raw materials by massfraction: 0.5 to 5.0 percent of American cockroach extract, 0.5 to 2 percent of watermelon cream, 0.2 to 1.5 percent of calcined gypsum, 0.1 to 1.0 percent of flos caryophyll extract, 1.0 to 5.0 percent of polyvinyl alcohol 17-88, 0.5 to 3.0 percent of sodium carboxymethyl cellulose, 0.4 to 1.0 percent of PEG-40 hydrogenated castor oil, 1.0 to 5.0 percent of glycerol and the balance of water. TheAmerican cockroach oral ulcer patch disclosed by the invention takes the American cockroach extract as a core functional component to inhibit the growth of pathogenic bacteria, so that infection is prevented and controlled; the American cockroach oral ulcer patch has the obvious effects of sterilizing and diminishing inflammation, clearing heat and detoxifying and relieving pain, and has the advantages of short treatment course, rapid effect, good curative effect and the like; the American cockroach oral ulcer patch has the effects of promoting ulcer healing, alleviating mucous membrane hyperemia and edema, and relieving oral ulcer symptoms. After oral ulcer is rehabilitated, the oral ulcer does not recur; the American cockroach oral ulcer patch is suitable for all people to use.

Description

technical field [0001] The invention relates to an oral ulcer medicine, in particular to a periplaneta americana oral ulcer patch and a preparation method thereof, belonging to the technical field of biomedicine. Background technique [0002] Oral ulcer, or aphth, is a common ulcerative injury disease that occurs in the oral mucosa, mostly in the inner lips, tongue, gums, soft palate and other parts. The prevalence of oral ulcers in the general population reaches more than 15%. When oral ulcers attack, it is often accompanied by burning pain. In severe cases, it will affect eating and speaking, and easily cause mood swings, thereby affecting the quality of life. There are many shortcomings in the treatment of oral ulcers with conventional oral medicines, such as wide action sites, large dosage, low drug utilization rate, and large bitter taste of drugs. In recent years, the oral ulcer patch is to disperse the drug in the solution containing bioadhesive materials to make a ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/61A61K9/70A61K47/44A61P1/02A61K33/06A61K35/64A61K36/42
CPCA61K47/44A61K9/006A61K33/06A61K35/63A61K36/42A61K36/61A61K2236/333A61K2300/00
Inventor 李映波黎静孙笠雯赵思聪
Owner 云南宁康生物科技有限公司
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