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Pharmaceutical composition for preventing and curing atherosclerosis

A technology of atherosclerosis and composition, applied in the field of medical preparations, can solve the problems of insignificant curative effect, achieve the effect of reducing the production of inflammatory cytokines and regulating lipid metabolism disorders

Active Publication Date: 2018-07-24
SOUTHERN MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The effective parts and monomers of traditional Chinese medicine are effective active ingredients extracted from traditional Chinese medicine. They are safe, effective and have few side effects, but the curative effect is often not significant when used alone

Method used

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  • Pharmaceutical composition for preventing and curing atherosclerosis
  • Pharmaceutical composition for preventing and curing atherosclerosis
  • Pharmaceutical composition for preventing and curing atherosclerosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0078] Weigh 150kg of geniposide, 150kg of notoginseng saponin R1, 5kg of dextrin, and 1kg of micropowder silica gel. Mix geniposide and notoginseng saponin R1 fine powder, then add dextrin and micropowder silica gel to make tablet. Take orally, two tablets each time, twice a day, take with warm water, a course of treatment for 12 weeks.

Embodiment 2

[0080] Weigh 200kg of geniposide, 100kg of notoginseng saponin R1, 2.5kg of dextrin, and 0.6kg of micropowder silica gel. Mix geniposide and notoginseng saponin R1 fine powder, then add dextrin and micropowder silica gel to make tablet. Take orally, two tablets each time, twice a day, take with warm water, a course of treatment for 12 weeks.

Embodiment 3

[0082] Weigh 100kg of geniposide, 200kg of notoginseng saponin R1, 3kg of dextrin, and 3kg of micropowder silica gel. Mix geniposide and notoginseng saponin R1 fine powder, then add dextrin and micropowder silica gel to make tablet. Take orally, two tablets each time, twice a day, take with warm water, a course of treatment for 12 weeks.

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Abstract

The invention relates to a pharmaceutical composition for preventing and curing atherosclerosis. The pharmaceutical composition is prepared from an effective constituent and a pharmaceutically accepted ingredient, and is characterized in that the effective constituent is prepared from the following raw materials with the following weight ratio: geniposide to notoginsenoside R1 in a ratio of (1 to2) to (2 to 1). The pharmaceutical composition has the effects of lowering blood lipid level, inhibiting inflammation and reducing atherosclerotic plaques, and has a remarkable effect on improvement of the atherosclerosis.

Description

field of invention [0001] The present invention relates to medical preparations containing organic active ingredients, in particular to pharmaceutical preparations containing carbohydrates, especially glycoside compounds. Background technique [0002] With the rapid development of social economy, the continuous improvement of living standards and the change of lifestyle, the global morbidity and mortality of cardiovascular diseases such as atherosclerosis are increasing year by year, and the coronary heart disease and stroke caused by it have become the It is one of the public health and social problems that cannot be ignored in the world, and it seriously threatens human health. Lipid metabolism disorders, especially cholesterol metabolism disorders, play an important role in the occurrence and development of atherosclerosis and the cardiovascular and cerebrovascular accidents it causes, and are also one of the independent risk factors for cardiovascular diseases such as co...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61K31/704A61P9/10
CPCA61K31/704A61K31/7048A61K2300/00
Inventor 贾钰华程赛博周凤华徐煜凌刘晓瑜陈育尧
Owner SOUTHERN MEDICAL UNIVERSITY
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