Primer set for identifying human Y chromosome typing, and applications, and product using primer set

A Y chromosome and primer set technology, which is applied in biochemical equipment and methods, recombinant DNA technology, and microbial determination/inspection, etc., can solve the problem that the number of Y chromosome STR loci cannot be effectively distinguished from male individuals of the same paternal line, and reduce the Limitations, improve detection efficiency, and reduce detection costs
CN108330177AInactive Publication Date: 2018-07-27HANGZHOU JILUO BIOLOGICAL PHARMA CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
HANGZHOU JILUO BIOLOGICAL PHARMA CO LTD
Publication Date
2018-07-27
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention provides a primer set for identifying human Y chromosome typing, and applications, and a product using the primer set, and relates to the field of biotechnology. According to the presentinvention, the primer set comprises 27 primer pairs and can amplify 29 human Y chromosome STR gene loci, wherein the 29 human Y chromosome STR gene loci contain the multiple rapid mutation sites on the Y chromosome, such that the limitation that the male individuals from the same male line cannot be effectively distinguished is reduced; and the kit for identifying human Y chromosome typing comprises the primer set, can quickly and accurately perform typing identification on human Y chromosome, and has high sensitivity and high specificity.
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Description

technical field

[0001] The invention relates to the field of biotechnology, in particular to a primer set for identifying human Y chromosome typing, an application thereof and a product using the same. Background technique

[0002] Among the 46 human chromosomes, the Y chromosome is the smallest G-group proximal centromere chromosome, containing about 59,000 kb of DNA. The length of the human Y chromosome is almost only 1 / 3 of the X chromosome. In different races and ethnic groups There is great variability in its length. The entire Y chromosome is mainly composed of the PAR region (pseudoautosomal region) and the male-specific region (male-specific region, MSY). During male meiosis, the pseudoautochromatic region can recombine with the X chromosome. The remaining 95% are specific regions of the Y chromosome.

[0003] Gene polymorphism (gene polymorphism) refers to the population in random mating, the same gene locus can have more than two genotypes. DNA site polymorphis...

Claims

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