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Cell transplantation pipe for nasal delivery and use method thereof

A technology of cell transplantation and intranasal drug delivery, applied in the field of medical devices, can solve the problem of no medical device products, and achieve the effects of reducing drug consumption, improving efficiency and reducing damage

Pending Publication Date: 2018-09-28
SHANGHAI ANGECON BIOTECH
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, there is no medical device product specially designed for cell drug delivery in the world

Method used

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  • Cell transplantation pipe for nasal delivery and use method thereof
  • Cell transplantation pipe for nasal delivery and use method thereof

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Embodiment Construction

[0028] The technical characteristics of the present invention will be further described below in conjunction with the accompanying drawings and specific embodiments.

[0029] like figure 1 A kind of cell transplantation tube for intranasal administration as shown, comprises a transplantation tube joint 1 communicated with a syringe and a transplantation hose 2 for transplanting cells to the nasal mucosa area rich in olfactory nerves below the cribriform plate deep in the nasal cavity; One end of the graft hose 2 is a connection end, and the connection end communicates with the graft tube joint 1 and is integrally formed; the other end of the transplant hose 2 is an intervention end, and the intervention end has a round head structure, and the distance from the intervention The side wall of the end 3mm is provided with a drug delivery hole 3; the diameter of the section of the drug delivery hole 3 decreases gradually from the outside to the inside.

[0030] The largest diamete...

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Abstract

The present invention discloses a cell transplantation pipe for nasal delivery and a use method thereof. The cell transplantation pipe for nasal delivery comprises a transplantation pipe joint which communicates with a syringe and a transplantation hose for transplanting cells into a nasal mucosa area enriched with olfactory nerve, wherein the transplantation hose is located under a sieve plate atthe deep portion of a nasal cavity. One end of the transplantation hose is a connecting end, and the connecting end communicates with the transplantation pipe joint to form one body. The other end ofthe transplantation hose is an intervention end, and the intervention end is of a circular head structure, a medicine delivery hole is formed in the side wall 2-4 mm away from the intervention end; and the diameter of the cross section of the medicine delivery hole decreases gradually from the outside to the inside. The cell transplantation pipe for the nasal delivery is specially designed for cell medicine delivery, and the technical scheme has the following beneficial effects that for cell transplantation into a central nervous system, compared with a traditional traumatic medicine deliverymethod, the nasal delivery can alleviate the pain of patients, reduce the injury of patients, and reduce the risk of patients; and a cell transplantation pipe can penetrate into the nasal cavity, themedicine wastage is reduced during medicine delivery, the nasal delivery efficiency is improved, the medicine wastage is small, and the cell transplantation pipe for nasal delivery is suitable for cell nasal delivery and other medicines which need low-dosage nasal delivery.

Description

technical field [0001] The invention relates to a cell transplantation tube, in particular to a cell transplantation tube for nasal administration and a method for using the same, belonging to the technical field of medical devices. Background technique [0002] Cell transplantation plays an important role in neural development and repair of damaged neural tissue. Cell transplantation is an effective method to repair and replace damaged brain tissue. It can rebuild part of the circuit and function, and has important clinical significance for the treatment of neurodegenerative diseases and central nervous system injury diseases. [0003] At present, there are two main ways for cell transplantation into the central nervous system: lumbar puncture, subarachnoid injection and head drilling injection. The former has less trauma, short time, and wide range of treatment, but there are still certain operational difficulties and risks; the latter Drilling one or two small holes in t...

Claims

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Application Information

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IPC IPC(8): A61M31/00
CPCA61M31/00A61M2202/09A61M2210/0618A61M2202/0007A61M2210/005
Inventor 姬广超王晓明郑佳威
Owner SHANGHAI ANGECON BIOTECH
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