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Method of providing an implantation site in soft tissue

A soft tissue and tissue technology, applied in the field of providing implantation sites and providing implantation sites in nerve tissue, can solve problems such as delayed dissolution or degradation

Active Publication Date: 2018-10-23
NEURONANO AB
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This can lead to adhesion of locally clotted blood to the matrix surface, which will significantly delay its dissolution or degradation, and thus the use of the microelectrode for its intended purpose

Method used

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  • Method of providing an implantation site in soft tissue
  • Method of providing an implantation site in soft tissue
  • Method of providing an implantation site in soft tissue

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0043] Example 1. First embodiment of the device of the invention

[0044] The device 1 of the invention has the form of a hollow pin 1 of elliptical cylinder (central axis B-B). The pins are substantially rigid and made of a suitable material such as metal or polymer. An axial duct or hole 6 in the pin 1 extends from the open proximal end 4' of the pin 1 to near the distal end 2' of the pin 1 where the duct 6 closes. The pin 1 comprises a central section C provided with a constant radius, which is arranged between a distal section D whose radius decreases towards the distal end 2' and a proximal section P P comprises an annular protrusion 5 for attaching a flexible pipe 8 . The central section C is provided with a radially extending hole 7 communicating with the central duct 6 and opening at the cylindrical outer surface of the pin 1 . Each set of holes comprising four holes is arranged in a radial plane at regular axial distance intervals. The illustrated arrangement of ...

example 2

[0045] Example 2. Second embodiment of the device of the invention

[0046] Using axial (D-D) and radial (E-E) sections in Figure 2a , 2b The second embodiment of the device 1 ′ of the invention in the form of a pin 1 ′ shown in FIG. The retaining element 10, and the axial length of the proximal section P exceeds the axial length of the central section C. Although the second embodiment is provided with a flexible tube corresponding to the tube 8 of the first embodiment at its proximal end, this tube is not included in the drawing for space-saving reasons. Figure 2a-2b shown in . The reference numbers 2', 3', 4', 6' and the reference letters D', C', P' correspond to the corresponding features 2, 3, 4, 6, D, C, P of the first embodiment.

[0047] exist Figure 2a , 2c and 2d, the pin 1' is mounted at the point where it is inserted into the soft tissue 14 by means of an insertion guide 17 comprising a sleeve 12 into the lumen of which the pin 1' can be inserted. The radi...

example 3

[0048] Example 3. A third embodiment of the device of the invention

[0049] adopted in Figure 1b A second embodiment 20 of the device of the invention in the form of a pin 20 shown in axial section roughly corresponds to figure 1The difference between the two is that the ring clamp 9 and the holding element 10 are omitted, and a conductor 21 is included, which is an electrode 21 or an optical fiber 21 arranged in the center of the catheter 6 . At its distal detection end 22, the electrode or fiber 21 is embedded in the distal portion P of the pin 20 in such a way that its distal face 22 forms a central section of the face of the distal portion P at the distal end 2' of the pin 20. . The electrode 21 is insulated (not shown) except at its distal end 2'. The conductor exits the conduit 6 laterally near its lateral end 4'.

[0050] For example, electrodes 21 or optical fibers 21 may be used to assist in the insertion of guide pin 20 to a desired depth by optically or electr...

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PUM

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Abstract

A method of providing a channel filled with aqueous gel in soft tissue comprises injecting a biocompatible aqueous gel into the tissue. Also disclosed is a corresponding device, the combination of thedevice and a guide for its insertion into tissue, and a system comprising the combination and a reservoir filled with aqueous gel comprising means for exerting pressure on the gel.

Description

Background technique [0001] The present invention relates to a method of providing an implant site in soft tissue, especially in nerve tissue, and a corresponding device. [0002] The object to be implanted may be a medical device or other object that is not physically stable enough for direct implantation by insertion into tissue. In particular, the medical device of the invention is a microelectrode or microprobe, such as an electrical or optical sensor. Objects to be implanted may also be living cells such as cultured cells, especially stem cells, as well as cell aggregates and living tissue pieces. Background technique [0003] The implantation of living cells such as stem cells, cell aggregates and tiny tissue masses obtained by culturing stem cells and other cells into soft tissues, particularly neural tissues, is problematic. Single cells run a high risk of being damaged during implantation, while cell aggregates or tissue fragments run the risk of being disassemb...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N1/05A61B5/04A61N1/36A61N1/372A61B5/24
CPCA61N1/0551A61B5/686A61B5/0084A61B2562/14A61B90/10A61B17/3468A61B5/24A61B2090/306A61B2560/063A61B2562/0209A61B2562/028A61B2562/146A61L27/222A61L2400/04A61L2400/06A61M25/007
Inventor J·舒恩伯格
Owner NEURONANO AB