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Bovine lncRNA-133a and its application and verification method in the regulation of proliferation and differentiation of bovine skeletal muscle satellite cells

A satellite cell and cell proliferation technology, applied in the field of molecular biology, can solve problems such as patent publications that have not yet been found, and achieve the effect of promoting proliferation, myogenic differentiation, and myogenic differentiation

Active Publication Date: 2021-12-14
TIANJIN AGRICULTURE COLLEGE
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

[0005] Through the search, no patent publications related to the patent application of the present invention have been found

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  • Bovine lncRNA-133a and its application and verification method in the regulation of proliferation and differentiation of bovine skeletal muscle satellite cells
  • Bovine lncRNA-133a and its application and verification method in the regulation of proliferation and differentiation of bovine skeletal muscle satellite cells
  • Bovine lncRNA-133a and its application and verification method in the regulation of proliferation and differentiation of bovine skeletal muscle satellite cells

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Embodiment Construction

[0036] The embodiments of the present invention will be described in detail below. It should be noted that the embodiments are illustrative, not restrictive, and cannot limit the protection scope of the present invention.

[0037] The raw materials used in the present invention, unless otherwise specified, are conventional commercially available products; the methods used in the present invention, unless otherwise specified, are conventional methods in the art.

[0038] A bovine lncRNA-133a, the nucleotide sequence of the bovine lncRNA-133a is SEQ1.

[0039] Further, the bovine lncRNA-133a has the function of promoting the proliferation and myogenic differentiation of bovine skeletal muscle satellite cells.

[0040] The application of bovine lncRNA-133a as described above in the regulation of proliferation and differentiation of bovine skeletal muscle satellite cells.

[0041] Further, the application is an application in promoting myogenic differentiation of bovine skeletal ...

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Abstract

The invention relates to a bovine lncRNA-133a sequence and its application and verification method in the regulation of proliferation and differentiation of bovine skeletal muscle satellite cells. The present invention provides a sequence of long-chain non-coding RNA lncRNA-133a related to bovine muscle development. The present invention finds for the first time that lncRNA-133a has the function of promoting the proliferation and myogenic differentiation of bovine skeletal muscle satellite cells, and can apply lncRNA-133a In regulation of proliferation and differentiation of bovine skeletal muscle satellite cells.

Description

technical field [0001] The invention belongs to the technical field of molecular biology, in particular to a bovine lncRNA-133a sequence and its application and verification method in regulating the proliferation and differentiation of bovine skeletal muscle satellite cells. Background technique [0002] Skeletal muscle is one of the most important tissues in the animal body, accounting for up to 40% of the body weight. Muscle cells are the basic unit of skeletal muscle, and their differentiation and development directly affect the development and formation of skeletal muscle. The differentiation, growth and development of muscle cells are the result of the interaction of internal genetics, epigenetics and external signals, and are finely regulated at multiple levels by the body's muscle development regulators and regulatory pathways. LncRNAs, as a kind of long non-coding RNA, can participate in many life processes such as cell growth and development. With the deepening of...

Claims

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Application Information

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IPC IPC(8): C12N15/113C12N5/10C12N5/077C12Q1/6888G01N33/68
CPCG01N33/68C12N5/0653C12N15/113C12Q1/6888C12N2506/1323C12N2310/10C12Q2600/158
Inventor 刘新峰郭宏丁向彬李新张林林李燕
Owner TIANJIN AGRICULTURE COLLEGE
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