Sequencing data processing method and device

A technology for sequencing data and processing methods, applied in the field of biological information, can solve the problems of slow comparison speed and low efficiency, and achieve the effect of reducing the time required for comparison and assembly

Active Publication Date: 2022-05-03
BEIJING NOVOGENE TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] Embodiments of the present invention provide a method and device for processing sequencing data, to at least solve the problem of slow comparison speed and low efficiency due to the need to use a large amount of resources and time to complete genome comparison in the process of genome assembly in the prior art. technical problem

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  • Sequencing data processing method and device
  • Sequencing data processing method and device
  • Sequencing data processing method and device

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Embodiment Construction

[0025] In order to enable those skilled in the art to better understand the solutions of the present invention, the following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only It is an embodiment of a part of the present invention, but not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present invention.

[0026] It should be noted that the terms "first" and "second" in the description and claims of the present invention and the above drawings are used to distinguish similar objects, but not necessarily used to describe a specific sequence or sequence. It is to be understood that the data so used are interchangeable under appropriate ...

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Abstract

The invention discloses a sequencing data processing method and device. Among them, the method includes: splitting the three-generation sequencing data to obtain at least one sub-sequencing data; comparing any sub-sequencing data to the corresponding reference genome to obtain the comparison result corresponding to any sub-sequencing data; For the result, get the merged result. The invention solves the technical problem that a large amount of resources and time are needed to complete the comparison of the genome in the process of genome assembly in the prior art, resulting in slow comparison speed and low efficiency.

Description

technical field [0001] The present invention relates to the technical field of biological information, in particular to a method and device for processing sequencing data. Background technique [0002] With the popularization of high-throughput sequencing technology, the genome maps of more and more species have been cracked. The genome is generally at the draft level, and generally consists of thousands to tens of thousands of scaffold sequences. [0003] At present, the commonly used software for connecting scaffolds based on the third-generation PacBio sequencing data is SSPACE-LongRead. It first uses blasr software to compare all reads to the genome, and obtains the comparison results of all reads and genome draft scaffolds. Then select the reads alignment results that can be aligned to multiple scaffolds at the same time, and then these third-generation sequencing reads connect two or more scaffolds into a long sequence at the alignment position and alignment direction...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G16B25/00
Inventor 许国良张锦波李季蒋智李瑞强
Owner BEIJING NOVOGENE TECH CO LTD
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