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Pharmaceutical composition for treating chicken mycoplasma synoviae and application thereof

A technology of mycoplasma synovialis and medicine, which is applied in the field of pharmaceutical compositions, can solve the problems of large influence on liver and kidney functions, liver and kidney dystrophy, etc., and achieves the effects of simple process, reduced use and easy realization.

Inactive Publication Date: 2018-11-23
SHENYANG VICA ANIMAL HUSBANDRY TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, vaccines are the mainstream method, but injection of oil vaccines has a great impact on liver and kidney function, causing liver and kidney failure, but does not reduce the incidence of the disease

Method used

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  • Pharmaceutical composition for treating chicken mycoplasma synoviae and application thereof
  • Pharmaceutical composition for treating chicken mycoplasma synoviae and application thereof
  • Pharmaceutical composition for treating chicken mycoplasma synoviae and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] The formula of embodiment 1 Chinese medicine combination

[0029] Eucommia 20-40 parts, Gentiana 10-30 parts, Fangji 10-20 parts, Caulis Spatholobus 10-20 parts, Guizhi 10-20 parts, Polygonum cuspidatum 10-20 parts, Astragalus 20-60 parts, Licorice 10-20 parts .

[0030] The traditional Chinese medicine combination is prepared from the following weights: Eucommia 20g, Gentiana 10g, Fangji 10g, Caulis Spatholobus 10g, Guizhi 10g, Polygonum cuspidatum 10g, Astragalus 20g, and Licorice 10g.

[0031] Or the traditional Chinese medicine combination is prepared from the following weights: Eucommia 40g, Gentiana 30g, Fangji 20g, Caulis Spatholobus 20g, Guizhi 20g, Polygonum cuspidatum 20g, Astragalus 60g, Licorice 20g.

[0032] Or the combination of traditional Chinese medicine is prepared from the following weights: Eucommia 33g, Gentiana 22g, Fangji 12g, Caulis Spatholobus 13g, Guizhi 12g, Polygonum cuspidatum 18g, Astragalus 42g, and Licorice 12g.

[0033] Or the combinat...

Embodiment 2

[0040] The preparation of embodiment 2 granules

[0041] The traditional Chinese medicine granules are composed of the following medicines by weight: Eucommia 30g, Gentiana 20g, Fangji 15g, Caulis Spatholobus 15g, Guizhi 15g, Polygonum cuspidatum 15g, Astragalus 40g, and Licorice 15g. Add 3 times the amount (weight ratio) of each of the traditional Chinese medicines for subsequent use. Decoct the above medicine twice at 10 times and 8 times, 40 minutes each time, combine the two decoctions, filter and concentrate to a relative density of 1.25-1.35 (25°C), add 380g sucrose and 125g dextrin to granulate , dried, and packaged.

Embodiment 3

[0042] Embodiment 3 preparation of oral liquid

[0043] The traditional Chinese medicine granules are composed of the following drugs by weight: Eucommia 30g, Gentiana 20g, Fangji 15g, Caulis Spatholobus 15g, Guizhi 15g, Polygonum cuspidatum 15g, Astragalus 40g, and Licorice 15g. Add 6 times the amount (weight ratio) of each of the traditional Chinese medicines for subsequent use. Decoct the above medicine twice at 10 times and 8 times, 60 minutes each time, combine the decoctions twice, filter and concentrate to 800ml, filter, add 1g of ethylparaben and 1g of stevia, stir to dissolve , add purified water to a volume of 1000ml, filter, add purified water to make up to 1000ml, subpackage, sterilize, and obtain.

[0044] It has been confirmed by pharmaceutical research that the preparation process is stable and suitable for mass production.

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Abstract

The invention relates to a pharmaceutical composition for treating chicken mycoplasma synoviae diseases. The pharmaceutical composition is prepared from the following raw materials in parts by mass: 20 to 40 parts of cortex eucommiae, 10 to 30 parts of radix gentianae macrophyllae, 10 to 20 parts of radix stephaniae tetrandrae, 10 to 20 parts of caulis spatholobi, 10 to 20 parts of cassia twig, 10to 20 parts of rhizoma polygoni cuspidati, 20 to 60 parts of radix astragali seu hedysari and 10 to 20 parts of liquorice root; the raw materials can be prepared into two preparations including granules and an oral solution. The traditional Chinese medicine composition provided by the invention has the effects of expelling wind and dispersing cold and eliminating dampness, promoting blood circulation, removing blood stasis and dredging collaterals, nourishing liver and kidney and strengthening body resistance to eliminate pathogenic factors, so that the effect of treating the chicken mycoplasma synoviae diseases is realized. Safety evaluation and clinical case application of the traditional Chinese medicine composition prove that the pharmaceutical composition has a remarkable effect of treating the chicken mycoplasma synoviae diseases, is a pure traditional Chinese medicine preparation, has high safety and a simple technology and is easy to popularize.

Description

Technical field: [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for treating Mycoplasma gallinarum and application thereof. technical background: [0002] Mycoplasma synoviae disease is also called chicken infectious synovitis. The disease mainly causes joint lesions and subclinical respiratory symptoms in chickens. It mainly invades the synovial bursa and tendon sheath of the joints. The typical symptoms are swelling of the tarsal joints and metatarsal joints, Limping, even deformation, sternal cyst, tenosynovitis and osteoarthritis, exudate in the joint cavity at the beginning of the disease, which is yellow or gray, clear and viscous, gradually becomes cloudy with the course of the disease, and finally becomes cheese-like, clinically Often co-infected with Mycoplasma gallisepticum at the same time. After the flock is infected, the immune function of the body is reduced, leading to an increase in susceptibility ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/704A61P31/04A61P19/04A61P19/02A61P29/00A61P1/12
CPCA61P1/12A61P19/02A61P19/04A61P29/00A61P31/04A61K36/46A61K36/481A61K36/484A61K36/486A61K36/515A61K36/54A61K36/59A61K36/704A61K2300/00
Inventor 王晓宇王方吴成伟赵宝凯
Owner SHENYANG VICA ANIMAL HUSBANDRY TECH
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