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Multi-vitamin effervescent tablet and preparation method thereof

A technology for vitamins and effervescent tablets, applied in the field of effervescent tablets, can solve the problems of bulging bags, splintering, easy moisture absorption, etc., and achieve the effects of convenient taking and carrying, uniform distribution and high solubility

Inactive Publication Date: 2018-12-11
江苏汉典生物科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation of effervescent tablets usually adopts the wet granulation process. The biggest disadvantage of the effervescent tablets produced by this method is that they are easy to absorb moisture or deliquesce, resulting in splits and bag swelling.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] 1. Multivitamin effervescent tablet, by weight percentage, it comprises the following components: vitamin A 0.08%, vitamin B 1 0.05%, vitamin B 2 0.05%, vitamin B 6 0.05%, vitamin B 12 0.0001%, vitamin C1.6%, vitamin E 0.44%, niacin 0.22%, calcium pantothenate 0.09%, folic acid 0.006%, citric acid 55%, sodium carbonate 24%, lactose 12.2439%, sweet orange essence 1.30%, sweet orange Fruit powder 3.0%, sorbitol 1.25%, sucralose 0.6%, acesulfame potassium 0.01%, sunset yellow 0.01%.

[0023] 2. The preparation method of the above-mentioned multivitamin effervescent tablet specifically comprises the following steps:

[0024] (1) Raw material preparation: take vitamin A and vitamin B of formula quantity 1 , Vitamin B 2 , Vitamin B 6 , Vitamin B 12 , vitamin C, vitamin E, niacin, calcium pantothenate, folic acid, citric acid, sodium carbonate, lactose, sweet orange essence, sweet orange fruit powder, sorbitol, sucralose, acesulfame potassium and sunset yellow pigme...

Embodiment 2

[0032] 1. Multivitamin effervescent tablet, by weight percentage, it comprises the following components: vitamin A 0.05%, vitamin B 1 0.1%, vitamin B 2 0.1%, vitamin B 6 0.1%, vitamin B 120.0001%, vitamin C 2.0%, vitamin E 0.3%, niacin 0.4%, calcium pantothenate 0.01%, folic acid 0.0099%, citric acid 50%, sodium carbonate 30%, lactose 13%, sweet orange essence 1.0%, sweet orange Fruit powder 1%, sorbitol 1%, sucralose 0.8%, acesulfame potassium 0.03%, sunset yellow 0.01%.

[0033] 2. The preparation method of the above-mentioned multivitamin effervescent tablet specifically comprises the following steps:

[0034] (1) Raw material preparation: take vitamin A and vitamin B of formula quantity 1 , Vitamin B 2 , Vitamin B 6 , Vitamin B 12 , vitamin C, vitamin E, niacin, calcium pantothenate, folic acid, citric acid, sodium carbonate, lactose, sweet orange essence, sweet orange fruit powder, sorbitol, sucralose, acesulfame potassium and sunset yellow pigment, crushed sepa...

Embodiment 3

[0042] 1. Multivitamin effervescent tablet, which comprises the following components by weight percentage: vitamin A 0.1%, vitamin B 1 0.01%, vitamin B 2 0.01%, vitamin B 6 0.0105%, vitamin B 12 0.0005%, vitamin C 1.0%, vitamin E 0.6%, niacin 0.1%, calcium pantothenate 0.1%, folic acid 0.005%, citric acid 58%, sodium carbonate 20%, lactose 10%, sweet orange essence 1.5%, sweet orange fruit powder 5%, Sorbitol 3%, Sucralose 0.524%, Acesulfame Potassium 0.01%, Sunset Yellow 0.03%.

[0043] 2. The preparation method of the above-mentioned multivitamin effervescent tablet specifically comprises the following steps:

[0044] (1) Raw material preparation: take vitamin A and vitamin B of formula quantity 1 , Vitamin B 2 , Vitamin B 6 , Vitamin B 12 , vitamin C, vitamin E, niacin, calcium pantothenate, folic acid, citric acid, sodium carbonate, lactose, sweet orange essence, sweet orange fruit powder, sorbitol, sucralose, acesulfame potassium and sunset yellow pigment, crus...

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Abstract

The invention relates to multi-vitamin effervescent tablet, which comprises, by weight, 0.05-0.1% of vitamin A, 0.01-0.1% of vitamin B1, 0.01-0.1% of vitamin B2, 0.01-0.1% of vitamin B6, 0.0001-0.0005% of vitamin B12, 1.0-2.0% of vitamin C, 0.3-0.6% of vitamin E, 0.1-0.4% of nicotinic acid, 0.05-0.1% of calcium pantothenate, 0.005-0.01% of folic acid, 50-60% of citric acid, 20-30% of sodium carbonate, 10-15% of lactose, 1.0-1.5% of orange flavor, 1-5% of orange fruit powder, 1-3% of sorbitol, 0.5-0.8% of sucralose, 0.01-0.03% of acesulfame potassium, and 0.01-0.03% of sunset yellow pigment. The prepared multi-vitamin effervescent tablet has characteristics of rapid disintegration and stable quality.

Description

technical field [0001] The invention belongs to the technical field of effervescent tablets, and in particular relates to multivitamin effervescent tablets and a preparation method thereof. Background technique [0002] In reality, many people have symptoms of vitamin deficiency, so they need to be treated with drugs in time. Any drug has certain side effects. Multi-vitamin effervescent tablets have almost no toxic side effects after long-term toxicological experiments. The product contains 13 kinds of vitamins needed by the human body, which are formulated according to the scientific ratio of human metabolism. Diseases caused by mineral deficiency can also improve the body's immunity and delay aging. It is suitable for people who are prone to fatigue, anemia, hepatitis, easy to be nervous, skin aging, easy to catch colds, gum inflammation, injured, drinking people, irritable, and smoking People, wounds are not easy to heal, subcutaneous bleeding is easy, fruit intake is i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/46A61K31/714A61P3/02A61K31/07A61K31/197A61K31/355A61K31/375A61K31/4415A61K31/455A61K31/51A61K31/519A61K31/525
CPCA61K9/0007A61K9/2009A61K9/2018A61K31/07A61K31/197A61K31/355A61K31/375A61K31/4415A61K31/455A61K31/51A61K31/519A61K31/525A61K31/714A61K2300/00
Inventor 丁向东严梦娟李祥菊
Owner 江苏汉典生物科技股份有限公司
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