Real-time measurement system and method for three-dimensional dosage distribution in human body
A three-dimensional dose, real-time measurement technology, applied in dosimeters, photographic dosimeters, etc., can solve problems such as limited sampling points, out-of-control primary tumors, local recurrence and radiation complications, and avoid the problem of dose disturbance and 3D dose measurement. accurate effect
Active Publication Date: 2018-12-11
CHINA INST FOR RADIATION PROTECTION
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Problems solved by technology
Due to limited sampling points, these methods cannot provide 3D dose verification with high spatial resolution in the relevant volume, so it is difficult to meet the dose verification requirements of new technologies for precision radiotherapy
With the popularization of dynamic radiation therapy techniques such as IMRT and VMAT, the steps in the treatment process have become very complicated, and dose control deviations in any link may lead to serious medical accidents
According to the International Commission on Radiation Units and Measurements (ICRU) No. 50 report, when the target dose deviates from the prescribed dose by ±5%, it may cause the primary tumor to go out of control (local recurrence) or increase radiation complications
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Embodiment 1
[0045] Such as figure 2 As shown, a real-time measurement device for three-dimensional dose distribution includes a physical model 1 , a main lens 2 , a Cmos camera detector 4 , and a microlens array 3 between the main lens 2 and the Cmos camera detector 4 . The position of the microlens array needs to be adjusted by combining the relevant parameters of the main lens 2 and the Cmos camera detector 4.
[0046] In this embodiment, the physical model 1 is composed of a shell made of high light-transmitting materials and tissue-equivalent scintillation gel materials. The thickness is generally between 0.1mm and 10mm. When the radiation produced by the radiation source undergoes energy deposition inside the physical model 1, luminescence information will be generated, and the light yield is proportional to the energy deposited in its volume, regardless of the dose rate at its location or the energy of the radiation itself.
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The invention discloses a real-time measurement system and method for three-dimensional dosage distribution in a human body, and the system comprises a human body organ physical model, a camera measurement system, and a dosage reconstruction system. The human body organ physical model comprises a human tissue equivalent housing, and a human tissue equivalent scintillator is disposed in the housing. According to the system and method provided by the invention, the scintillator can be used as a detector, and also plays a role of a die body, thereby solving a problem of dosage disturbance causedby the introduction of the detector into the model, and enabling the three-dimensional dosage measurement to be more accurate. The camera measurement system is used for collecting the light generatedby the scintillator at the speed of several frames per second or even dozens of frames per second and a dosage reconstruction algorithm, and can achieve the real-time reconstruction of the three-dimensional dosage distribution.
Description
technical field [0001] The invention relates to the technical field of radiotherapy and dose verification, in particular to a real-time measurement system and method for three-dimensional dose distribution inside a human body. Background technique [0002] At this stage, many aspects of the nuclear industry, such as the study of radiation damage, the effects of radiation on the human body, etc., need to provide comprehensive three-dimensional dose distribution data inside the human body. The traditional method is to use the equivalent physical model of human tissue, in which The dose is measured by punching holes and inserting a thermoluminescent dosimeter (TLD) inside, so the dose data obtained in this way is discontinuous, and the insertion of the dosimeter will also disturb the dose. [0003] In addition, in the field of radiotherapy, as a key part of quality assurance and control, radiation dose verification before treatment can not only effectively reduce the risk of er...
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IPC IPC(8): G01T1/08
CPCG01T1/08
Inventor 李华李德源牛蒙青闫学文戴雄新张小东
Owner CHINA INST FOR RADIATION PROTECTION