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Magnetic bead separation device, separation method and electrochemical immune analyzer

A magnetic bead separation and separation method technology, applied in the direction of measuring devices, scientific instruments, analytical materials, etc., can solve the problems of reduced detection sensitivity and reliability, magnetic beads cannot be directly detected, poor compatibility of devices, etc., and achieve compact structure , Reduce the cost of detection, reduce the effect of test error

Pending Publication Date: 2018-12-25
天津博硕科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, it has certain disadvantages: the separated magnetic beads cannot be directly detected, the compatibility of the device is poor, and it will cause the loss of magnetic beads, reducing the detection sensitivity and reliability

Method used

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  • Magnetic bead separation device, separation method and electrochemical immune analyzer
  • Magnetic bead separation device, separation method and electrochemical immune analyzer
  • Magnetic bead separation device, separation method and electrochemical immune analyzer

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Embodiment Construction

[0036] It should be noted that, in the case of no conflict, the embodiments of the present invention and the features in the embodiments can be combined with each other.

[0037] In describing the present invention, it should be understood that the terms "center", "longitudinal", "transverse", "upper", "lower", "front", "rear", "left", "right", The orientations or positional relationships indicated by "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. are based on the orientation or positional relationships shown in the drawings, and are only for the convenience of describing the present invention Creation and simplification of description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore should not be construed as limiting the invention. In addition, the terms "first", "second", etc. are used for descriptive purposes only, and should no...

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Abstract

The invention provides a magnetic bead separation device, separation method and an electrochemical immune analyzer. The magnetic bead separation device comprises a reaction liquid pipeline, a sterilewater pipeline and a separation liquid pipeline, wherein the sterile water pipeline and the separation liquid pipeline communicate with the reaction liquid pipeline; a plurality of third electromagnets are sequentially arranged on the reaction liquid pipeline, and a separation pipe total electromagnetic valve is arranged on the separation liquid pipeline on the right side of the third electromagnet at the rightmost end; the tail end of the reaction liquid pipeline protrudes from the sterile water pipeline to form a protruding part, and a fourth electromagnet is arranged on the protruding part;and immune magnetic beads move towards the tail end of the reaction liquid pipeline by controlling the on-off of a first electromagnet, and a second giant magnetoresistive chip module is arranged onthe separation liquid pipeline in a sleeving mode. The separation device created drives the immune magnetic beads to move towards the tail end of the reaction liquid pipeline by performing time sequence on-off control over the electromagnets, so that compared with the common liquid drive, the separation is more thorough; and after the magnetic beads are separated, the separation pipeline is backward flushed, the pipeline is cleaned more thoroughly, online separation is realized, the separation speed is faster, and the separation efficiency is improved.

Description

technical field [0001] The invention belongs to the technical field of immunomagnetic beads, and in particular relates to a magnetic bead separation device, a separation method and an electrochemical immunoassay analyzer. Background technique [0002] At present, immunomagnetic bead technology has been widely used in the detection of microorganisms, cells, chemical elements and other targets in food, clinical, soil and other environments. Since the accuracy of magnetic bead separation directly affects the final detection effect, for the detection process The magnetic bead separation problem puts forward higher requirements. At this stage, there are some disadvantages in the cleaning and separation process of immunomagnetic beads, not only the structure is cumbersome but also a large amount of magnetic beads are lost during the separation process. [0003] Chinese patent CN204422539U discloses a magnetic bead cleaning and separation device for a fully automatic chemiluminesc...

Claims

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Application Information

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IPC IPC(8): G01N33/543
CPCG01N33/54326
Inventor 杜康刘新全李祎璠孙兆敏
Owner 天津博硕科技有限公司
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