Pharmaceutical composition for relieving cough, reducing phlegm and relieving asthma and its preparation
A technology of pharmaceutical preparations and compositions, applied in the direction of pharmaceutical combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc., which can solve problems such as adverse reactions and deaths
Active Publication Date: 2021-02-05
GUANGDONG FOOD & DRUG VOCATIONAL COLLEGE
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- Summary
- Abstract
- Description
- Claims
- Application Information
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Problems solved by technology
Dextromethorphan is safe and effective in suppressing cold symptoms when used correctly in small doses, but overuse can cause death and other serious adverse effects such as brain damage, seizures, loss of consciousness and irregular heartbeats, the U.S. Food and Drug Administration said.
Method used
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Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0026] Take sibetin 25g, quercetin 100g. First mix 25 g of sibetin with 30 g of starch, then mix with 100 g of quercetin, then add 2 g of micropowdered silica gel, mix evenly, and put it into 1000 capsules to obtain capsules.
Embodiment 2
[0028] Take 25g of sibetin, 100g of quercetin, add 30g of starch and mix evenly, then add 2g of micropowdered silica gel, mix evenly, put into 1000 capsules to obtain capsules.
Embodiment 3
[0030] Take sibetin 25g, quercetin 100g. First mix 100g of quercetin with 130g of starch, then mix with sibetin, wet granulate, dry the granules, add 2g of micro-powdered silica gel, mix well, press into 1000 tablets to obtain tablets.
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Abstract
The invention relates to a pharmaceutical composition for relieving cough, reducing phlegm and relieving asthma, which comprises sibetin and quercetin. After a lot of research, it is found that Sibetin and Quercetin have a synergistic effect, and the pharmaceutical composition formed by combining Sibetin and Quercetin has a good effect of relieving cough, reducing phlegm and relieving asthma. Moreover, further adopting a suitable dosage ratio, the synergistic effect of the two can be brought into play very well.
Description
technical field [0001] The invention belongs to the field of medicaments, and relates to a pharmaceutical composition for relieving cough, reducing phlegm and relieving asthma and its preparation. Background technique [0002] Imperialine is one of the important alkaloids contained in Fritillaria japonicus, and it is used together with monomer alkaloids in Fritillaria siberiana to prepare antitussive, expectorant and / or anti-inflammatory drugs. [0003] Quercetin, also known as quercetin, quercetin, soluble in glacial acetic acid, the alkaline aqueous solution is yellow, almost insoluble in water, and the ethanol solution tastes very bitter. It can be used as a medicine. Some reports believe that it has expectorant and cough-relieving effects, and has a certain anti-asthma effect. It is also used to treat chronic bronchitis. [0004] Cough and expectoration are two common symptoms of respiratory system diseases, which are closely related pathologically. Generally, cough wit...
Claims
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IPC IPC(8): A61K31/4375A61K31/352A61K9/48A61P11/14A61P11/10A61P11/06
CPCA61K9/48A61K31/352A61K31/4375A61P11/06A61P11/10A61P11/14A61K2300/00
Inventor 焦豪妍汤庆发郑海沈小钟邱蔚芬崔穗旭
Owner GUANGDONG FOOD & DRUG VOCATIONAL COLLEGE