Device for noninvasive determination of pathophysiological conditions
A technology of illuminator and detector, which is applied in the fields of eye testing equipment, material excitation analysis, medical science, etc., and can solve the problem of no portable and easy-to-operate device or method
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example 1
[0029] Example 1 is an apparatus comprising: a data collection system comprising: an illuminator, a detector, and a beam splitter operatively coupled to the detector; an actuation assembly coupled to the illuminator via a bracket, The actuation assembly includes an electric motor coupled to a linear actuator; and a visible target to facilitate alignment of the subject's eyes with the data collection system; wherein the illuminator illuminates interrogating radiation to target tissue, and the an actuation assembly moves the illuminator from a first position to a second position to scan the focal point of the interrogating radiation through a predetermined thickness of target tissue; and wherein the detector detects at least one value of at least one characteristic of the response radiation.
[0030] In Example 2, the subject matter of Example 1 optionally includes wherein the response radiation comprises backscattered light, Rayleigh light, fluorescence, or light produced by th...
example 23
[0051] Example 23 is a method comprising: facilitating self-alignment of a target tissue of a subject relative to an apparatus comprising: an illuminator, a detector, and a beam splitter operably coupled to the detector an actuation assembly coupled to the illuminator via a bracket, the actuation assembly including a motor coupled to a linear actuator; and facilitating interaction of the subject's eyes with the data collection system an accurate visible target; monitor the target tissue until the target tissue corresponds to a target location; illuminate the target tissue with the illuminator; move the illuminator from a first position to a second position via the actuating assembly, scanning interrogation light through a focal point of a predetermined thickness of target tissue; detecting at least one characteristic of responsive radiation received or reflected from said target tissue; and correlating at least one characteristic of said responsive radiation to determine condit...
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