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A preparation method of a pharmaceutical composition for treating frequent micturition

A composition and drug technology, applied in the field of pharmaceutical composition preparation, can solve the problems of expensive, obvious side effects, and single effect, and achieve the effect of low cost, small side effects, and simple preparation method

Inactive Publication Date: 2019-01-15
罗丰兵
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, most of the drugs on the market are single-effect, expensive, and have obvious side effects, so there is an urgent need to research and develop a compound drug for treating frequent urination with good curative effect, low cost, and few side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Party:

[0018] 30 parts of tangerine peel, 25 parts of citrus aurantium, 15 parts of citrus aurantium, 10 parts of psyllium, 10 parts of capillary wormwood, 2 parts of tea, 3 parts of tomato.

[0019] Preparation:

[0020] (1) The above-mentioned raw materials are weighed according to the formula ratio, and the dried tangerine peel, citrus aurantium and citrus aurantium are crushed through a 120-mesh sieve, immersed in water, decocted with a slow fire, combined with decoction and filtered to obtain filtrate A;

[0021] (2) Dry and grind the psyllium seed, Artemisia capillary, tea leaves, and spicy eggplant after drying, pass through a 60-mesh sieve, add distilled water twice the total weight of the plantago seed, Artemisia capillary, tea leaf, and spicy eggplant, and heat to boil. Filter, and filtrate B is standby;

[0022] (3) Mix filtrate A and filtrate B, add ethanol with a volume fraction of 70% and soak for 2 hours, after the ethanol is completely volatilized, a...

Embodiment 2

[0025] Party:

[0026] 48 parts of tangerine peel, 35 parts of citrus aurantium, 25 parts of citrus aurantium, 18 parts of psyllium, 15 parts of capillary wormwood, 4 parts of tea, 5 parts of tomato.

[0027] Preparation:

[0028] (1) The above-mentioned raw materials are weighed according to the formula ratio, and the dried tangerine peel, citrus aurantium and citrus aurantium are crushed through a 150-mesh sieve, immersed in water, decocted with a slow fire, combined with decoction and filtered to obtain filtrate A;

[0029] (2) Dry and grind the psyllium seed, Artemisia capillary, tea leaves, and spicy eggplant after drying, pass through an 80-mesh sieve, add distilled water 4 times the total weight of the plantago seed, Artemisia capillary, tea leaf, and spicy eggplant, and heat to boil. Filter, and filtrate B is standby;

[0030] (3) Mix filtrate A and filtrate B, add ethanol with a volume fraction of 80% and soak for 4 hours, after all ethanol volatilizes, add distille...

Embodiment 3

[0033] Party:

[0034] 38 parts of tangerine peel, 32 parts of citrus aurantium, 22 parts of citrus aurantium, 16 parts of psyllium, 13 parts of wormwood, 3 parts of tea, 4 parts of tomato.

[0035] Preparation:

[0036] (1) The above-mentioned raw materials are weighed according to the formula ratio, and the dried tangerine peel, citrus aurantium and citrus aurantium are crushed through a 135-mesh sieve, immersed in water, decocted with a slow fire, combined with decoction and filtered to obtain filtrate A;

[0037] (2) Dry and grind the psyllium seed, Artemisia capillary, tea leaves, and spicy eggplant after drying, pass through a 70-mesh sieve, add distilled water three times the total weight of the plantago seed, Artemisia capillary, tea leaf, and spicy eggplant, and heat to boil. Filter, and filtrate B is standby;

[0038] (3) Mix filtrate A and filtrate B, add ethanol with a volume fraction of 75% and soak for 3 hours, after all the ethanol volatilizes, add distilled w...

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PUM

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Abstract

The invention discloses a preparation method of a pharmaceutical composition for treating frequent micturition, comprising the following steps: (1) pulverizing and sieving dried orange peel, orange fruit and immature orange fruit, immersing medicine powder with water, decocting the mixture with soft fire, performing filtration to obtain a filtrate A; (2) drying and then grinding plantain seed, virgate wormwood herb, tea leaves and hot pepper, sieving the mixture, adding distilled water the weight of which is 2-4 times of the total weight of the plantain seed, virgate wormwood herb, tea leavesand hot pepper, heating and boiling the mixture, cooling the mixture, and then filtering the mixture to obtain a filtrate B; (3) mixing the filtrate A and filtrate B, adding ethanol, soaking, adding distilled water, uniformly mixing, concentrating and drying to obtain concentrate C; (4) adding adjuvant of the concentrate C to prepare the finished product dosage form required by clinic. Compared with the prior art, the preparation method is simple, saves labor and cost, can maximize the utilization of raw materials, and improves the bioavailability. The pharmaceutical composition for treating urinary frequency prepared by the method has the advantages of good curative effect, low cost and small side effect, and is suitable for most frequent micturition patients.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a preparation method of the pharmaceutical composition for treating frequent urination. Background technique [0002] Normal adults urinate 4 to 6 times during the day and 0 to 2 times at night, and the frequency increases significantly, which is called frequent urination. Frequent urination can be either physiological, psychoneural, or one of the symptoms of many diseases. There are many reasons for frequent urination, including inflammation, foreign bodies, mental factors, physical weakness after illness, and parasitic diseases. The following situations are common: (1) Polyuria, frequent urination, increased frequency of urination and a large amount of urine each time, and the total urine output throughout the day increased. Seen in diabetes, diabetes insipidus, psychotic polydipsia and polyuria phase of acute renal failure. (2) Inflammatory frequent urination is small in urin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/82A61P13/00
CPCA61K36/752A61K36/282A61K36/68A61K36/81A61K36/82A61K2236/331A61K2236/333A61K2300/00
Inventor 罗丰兵
Owner 罗丰兵