A dedicated high-efficiency rack for automatic release rate sampling system
A sampling system and automatic release technology, applied in the direction of material inspection products, testing pharmaceutical preparations, etc., can solve the problems of experimental time error and inaccurate experimental data, so as to delay the experimental time, avoid inaccurate experimental data, and achieve good experimental results Effect
Active Publication Date: 2021-06-04
LUGEN INSTR ZHENJIANG
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Problems solved by technology
[0007] Therefore, when performing dissolution experiments, it is often necessary to fully simulate various parts of the stomach and intestinal tract. This process requires the use of multiple or even multiple solvent outer tubes to simulate the environment. Most of them use the same solvent outer tube. When changing the environment of the drug, it is necessary to take out the drug basket and replace the solvent outer tube. In this way, there will be errors in the experimental time, which will easily lead to inaccurate experimental data.
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[0040] It can be seen from the accompanying drawings that a high-efficiency rack dedicated to the automatic release rate sampling system is characterized in that it includes a base, a vertical movement mechanism, a horizontal movement mechanism, a sampling support, an inner tube placement rack, and a solvent outer tube placement plate;
[0041]The base is used to install the horizontal movement mechanism, the vertical movement mechanism and the water tank of the sampling system; the base includes a bottom plate and side plates, and the number of the side plates is two, which are vertically symmetrically distributed and fixed on both sides of the bottom plate, The water tank is installed and fixed between the two side plates; the tops of the two support columns on one side of the base are fixedly connected to the support plate of the outer solvent tube, and each of the support plates of the outer solvent tube is fixed with several sets of fixed protrusions groups, each group of ...
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A dedicated high-efficiency rack for an automatic release rate sampling system, characterized in that it includes a base, a vertical movement mechanism, a horizontal movement mechanism, a sampling support, an inner tube placement rack, and a solvent outer tube placement plate; Intestinal peristalsis, the inner tube moves up and down inside the solvent outer tube, using the solvent outer tube to simulate the gastrointestinal environment inside the human body, the inner tube moves up and down inside the solvent outer tube, the dissolution is strong, and on the other hand, it is more suitable for gastrointestinal peristalsis It is more appropriate to use up and down motion to simulate the environment of gastrointestinal motility, and the experimental effect is better.
Description
technical field [0001] The invention belongs to the technical field of medical experiment equipment application, in particular to a special high-efficiency rack for an automatic release rate sampling system. Background technique [0002] In order to produce a desired pharmacological effect, the drug must be made available in the body at an appropriate concentration at its site of action. This effectiveness is influenced by a variety of factors including: the amount of drug administered, the rate of drug absorption, distribution (binding or localization) in tissues, drug metabolism, and elimination from the body. [0003] As an inspection method for drug properties, dissolution testing plays an important role in the quality consistency evaluation of generic drug preparations and changes after approval. The United States Pharmacopoeia divides drug dissolution release devices into 1-7 methods, of which the third method is the reciprocating cylinder method, which is used for th...
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IPC IPC(8): G01N33/15
CPCG01N33/15
Inventor 李定中宋水军姚鹏志
Owner LUGEN INSTR ZHENJIANG