Device for quantitative intranasal brain targeting drug delivery and drug storage containers

Abstract

The invention discloses a device for quantitative intranasal brain targeting drug delivery and drug storage containers. The device comprises a sprayer and a bottle body, the sprayer is fixedly connected with or detachably mounted on the bottle body, the bottle body is internally provided with a drug delivery chamber, a gas extrusion chamber and a containing chamber for storing drug modules separately, a partition plate which can be inserted and pulled out is arranged between the drug delivery chamber and the containing chamber, and the containing chamber is also internally provided with a cartridge-like structure used for pushing the drug modules toward the drug delivery chamber; each drug module comprises the corresponding sealed drug storage container filled with drugs, the container wall of each drug storage container is made of a hard material, and the portion, corresponding to an inlet end of a drug delivery pipe and a gas outlet end of a vent pipe I, of each container wall is provided with a sealed film-like structure. The device is detachable, modular in design and convenient to assemble, use, clean and maintain, the sprayer of the drug delivery device can be disassembled, the device can be used exclusively for special people, and regular updating can also prevent drug contamination and cross infection. The detachability of the drug device provides convenience for storage and management, and the device is suitable for being assembled for troops.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and in particular relates to a device and a drug storage container for quantitative targeted drug delivery through the nose and brain. Background technique [0002] The blood-brain barrier is a layer of natural barrier between the systemic circulation and the central nervous system. While playing a barrier role, preventing pathogenic microorganisms and harmful substances from entering the brain, it also prevents many drugs from entering the central nervous system through the blood circulation to play a therapeutic role. . Many current drug delivery methods, such as transcranial in situ injection and subarachnoid injection, are difficult to be widely used in clinical practice due to strong trauma and high technical requirements for operation. [0003] The terminal branch of the olfactory nerve is distributed in the olfactory mucosa. As one of the 12 pairs of cranial nerves, its existence ...

AI Technical Summary

Problems solved by technology

However, many devices do not have a part to prevent backflow, and directly communicate with the outside world, which increases the possibility of drug contamination and deterioration, and reduces the validity period of the drug.

And the nasal cavity is a bacterial environment, long-term use of the device has the risk of secondary infection

And most of the integrated devices are difficult to disassemble, so the obstacle of cleaning and care will also lead to the occurrence of pollution

Moreover, once produced, the built-in medicine cannot be replaced, and there is often no possibility of reusing the device after use, which leads to a waste of resources to a certain extent.

The design of the device combined with the ultrasonic atomization device for drug delivery is complex and expensive, and the effectiveness of the ultrasonic device has yet to be proven

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