The invention discloses a high-efficiency sustained-release agricultural chemical and a production process thereof. The agricultural chemical comprises an effective active core layer, a sandwich filmcoating layer and a bio-release permeable membrane layer from the inside to the outside. The effective active core layer is prepared from following raw materials by mass: an agricultural chemical active ingredient, humic acid, auxiliaries, diatomite, a dispersant and cellulose. The sandwich film coating layer is prepared from deionized water, sodium alginate, ethyl cellulose, polyvinyl alcohol andglycerin. The bio-release permeable membrane layer is prepared from cellulose acetate fibers, shrimp shell powder, argy wormwood leaf powder, polyacrylamide, mineral oil, polyhydroxyalkanoate and sodium dodecylbenzenesulfonate. The effective active core layer is prepared by mixing and granulation, the sandwich film coating layer is prepared by spraying, coating and curing, and a product covered with the sandwich film coating layer is subjected to immersion, curing and shaping to prepare a finished product. The prepared product has good sustained-release effects, can resist erosion and erosioncaused by water, and can avoid drug contamination of water bodies and plant fruits.