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Gel containing heparin-like composition

A technology of composition and gel, which is applied in the field of gel containing heparan-like composition, can solve problems such as imperfect application of heparan-like composition, and achieve inhibition of smooth muscle cell proliferation, promotion of supply and excretion of waste, inhibition of The effect of overgrowth

Inactive Publication Date: 2019-03-22
沈阳亿欣源生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, in the prior art, the application of the heparinoid composition on the skin, mucous membrane and other action sites is not perfect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Example 1: A gel containing a heparinoid composition, including 30 parts of heparin, 66 parts of matrix material, 0.1 part of dimethyl sulfoxide, 0.1 part of vitamin C, 0.1 part of potassium sorbate, and 0.5 parts of collagen parts, 3 parts of glycerin, and 0.18 parts of preservatives.

Embodiment 2

[0026] Example 2: A gel containing a heparinoid composition, including 10 parts of heparin, 86 parts of matrix material, 1 part of dimethyl sulfoxide, 0.125 parts of vitamin C, 0.125 parts of potassium sorbate, and 10 parts of collagen 10 parts of glycerin, 2 parts of preservatives.

Embodiment 3

[0027]Example 3: A gel containing a heparinoid composition, including 5 parts of heparin, 90 parts of matrix material, 2 parts of dimethyl sulfoxide, 0.2 parts of vitamin C, 0.2 parts of potassium sorbate, and 20 parts of collagen 15 parts of glycerin, 5 parts of preservatives.

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PUM

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Abstract

The invention discloses a gel containing a heparin-like composition, and belongs to the field of biotechnology. The gel containing the heparin-like composition is characterized by comprising 0.01-30 parts of mucopolysaccharide, 30-90 parts of a matrix material, 0.01-5 parts of a transdermal absorbent, 0.01-5 parts of an antioxidant, 0.01-5 parts of a bacteriostatic agent, 0.01-15 parts of a surfactant and 0.01-5 parts of a preservative. Under a synergistic action of a keratin softening agent and a natural moisturizing agent, the gel containing the heparin-like composition can inhibit the excessive growth of collagen fiber and reduce scar formation; the gel containing the heparin-like composition can retain moisture on the surface of skin to soften the collagen fiber and enhance the elasticity and has an effect of softening a hypertrophic scar.

Description

technical field [0001] The invention belongs to the field of biotechnology, and in particular relates to a gel containing a heparin-like composition used in medicines, medical equipment, cosmetics, disinfection products and the like. Background technique [0002] Heparinoid is a mucopolysaccharide. In 1948, when Jorpes and Gardell prepared heparin from liver and lung, they obtained a polysaccharide composed of D-glucuronic acid and D-glucosamine. These substances are similar in structure to heparin , but the degree of sulfation is low, and the anticoagulant activity is low, but after more sulfation, its properties change greatly. By combining with the surface of vascular endothelium, it promotes the release of endogenous amino polysaccharides with antithrombotic activity, which can improve local microcirculation, increase blood flow and blood flow velocity, thereby improving intermediate metabolism, promoting skin nutrition supply and waste excretion , play a role in reduci...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K47/42A61K31/726A61K31/727A61K31/737A61P29/00A61P31/04A61P31/10A61P31/12A61P7/10A61P17/02
CPCA61K9/0014A61K9/06A61K31/726A61K31/727A61K31/737A61K47/42A61P7/10A61P17/02A61P29/00A61P31/04A61P31/10A61P31/12
Inventor 唐财坤关云成李丹徐巍张锡玮满国荣朱凯月肖秀梅马立强
Owner 沈阳亿欣源生物科技有限公司
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