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Algal polysaccharides plant soft capsules and preparation method thereof

A technology of seaweed polysaccharides and soft capsules, which is applied in the direction of capsule transportation, etc., can solve the problems of not being able to use pig products, limit the use of gelatin, and aging of gelatin, and achieve shortened disintegration time, avoid sticking and clumping, good elasticity and stability Effect

Inactive Publication Date: 2019-03-29
JIANGSU ZODIAC MARINE BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, domestic soft capsules are mainly produced with gelatin as raw material. Gelatin is an excellent thermally reversible gelling agent. However, soft capsules made of gelatin usually have delayed disintegration, which is mainly due to the The gelatin in the gelatin is affected by low-molecular-weight aldehydes and the oxidation process to produce a cross-linking reaction that causes the aging of the gelatin.
In addition, since gelatin is mostly extracted from the skin and bones of pigs and cows, and Hebrews, Muslims, vegetarians, etc. cannot use pig products, and gelatin products do not indicate their animal origin, thus limiting the use of gelatin use
In addition, the existence of diseases such as mad cow disease and foot-and-mouth disease makes the use of gelatin as the capsule shell of soft capsules to have certain safety risks

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] According to the mass ratio of centipede algae carrageenan and k-type carrageenan as 1:1, prepare seaweed polysaccharide gum 60g; Tianqing gum 7g; glycerol 1g; calcium chloride 0.01g.

[0023] 1g of glycerol is dissolved in deionized water to obtain the first solution; 60g of seaweed polysaccharide gum and 7g of Tianqing gum are added to the first solution, and the seaweed polysaccharide gum comprises centipede algae carrageenan with a mass ratio of 1:1 K-type carrageenan, after stirring evenly, add 0.01g of calcium chloride, heat up to 70°C, continue to stir until the jelly is completely dissolved, stir and keep warm for 20 minutes, then cool down to 50°C, vacuumize until no bubbles are generated, and obtain the glue liquid.

[0024] Filter the glue with a mesh number of 80, and then press the glue into capsules by conventional pressing method, where the capsules are wet capsules. The wet capsule was dried for 12 hours at a temperature of 30°C and a relative humidity ...

Embodiment 2

[0027] According to the mass ratio of centipede algal carrageenan and k-type carrageenan as 2:1, prepare seaweed polysaccharide gum 70g; Tianqing gum 12g; 2,4-hexadienol 3g; calcium chloride 0.03g.

[0028] 3g of 2,4-hexadienol was dissolved in deionized water to obtain a first solution; 70g of seaweed polysaccharide gum and 12g of Tianqing gum were added to the first solution, and the seaweed polysaccharide gum included centipede polysaccharides with a mass ratio of 2:1 Algae carrageenan and k-type carrageenan, after stirring evenly, add 0.03g of calcium chloride, heat up to 80°C, continue to stir until the jelly is completely dissolved, keep stirring for 25 minutes, cool down to 55°C, and vacuum until there are no bubbles Generate, get the glue.

[0029] The above-mentioned glue solution is filtered through a filter screen with a mesh number of 90, and then the glue is hydraulically formed into capsules by conventional pressing method, and the capsules here are wet capsules....

Embodiment 3

[0032] According to the mass ratio of centipede algae carrageenan and k-type carrageenan as 4:1, prepare seaweed polysaccharide gum 80g; Tianqing gum 14g; glycerin 5g; zinc chloride 0.05g.

[0033] 5g glycerol is dissolved in deionized water to obtain the first solution; 80g seaweed polysaccharide gum and 14g Tianqing gum are added to the first solution, and the seaweed polysaccharide gum comprises centipede algae carrageenan and carrageenan with a mass ratio of 4:1 K-type carrageenan, after stirring evenly, add 0.05g of zinc chloride, heat up to 90°C, continue to stir until the jelly is completely dissolved, stir and keep warm for 30min, then cool down to 60°C, vacuumize until no bubbles are generated, and obtain the glue liquid.

[0034] The above-mentioned glue solution is filtered through a filter screen with a mesh number of 100, and then the glue solution is hydraulically formed into capsules by a conventional pressing method, and the capsules here are wet capsules. The...

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Abstract

The invention relates to algal polysaccharides plant soft capsules and a preparation method thereof. The algal polysaccharides plant soft capsules comprise the following components in percentage by mass: 60%-80% of algal polysaccharides gum, 7%-14% of galactomannan gum, 1%-5% of a plastifier, 0.01%-0.05% of a coagulant and the balance of deionized water. According to the algal polysaccharides plant soft capsules disclosed by the invention, the galactomannan gum has great affinity to water, so that the disintegration time of the algal polysaccharides plant soft capsules can be shortened, and inthe preparation process of the algal polysaccharides plant soft capsules, cohering and clustering phenomena between gum powder can be avoided.

Description

technical field [0001] The invention relates to the technical field of capsule preparation, in particular to a seaweed polysaccharide plant soft capsule and a preparation method thereof. Background technique [0002] At present, domestic soft capsules are mainly produced with gelatin as raw material. Gelatin is an excellent thermally reversible gelling agent. However, soft capsules made of gelatin usually have delayed disintegration, which is mainly due to the The gelatin in the gelatin is affected by low-molecular-weight aldehydes and the oxidation process to produce a cross-linking reaction that causes the aging of the gelatin. In addition, since gelatin is mostly extracted from the skin and bones of pigs and cows, and Hebrews, Muslims, vegetarians, etc. cannot use pig products, and gelatin products do not indicate their animal origin, thus limiting the use of gelatin use. In addition, the existence of diseases such as mad cow disease and foot-and-mouth disease makes the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K47/36
CPCA61K9/4816A61K47/36
Inventor 聂毅宗有田
Owner JIANGSU ZODIAC MARINE BIOTECH
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