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Application of Dendrobium officinale leaves, sealwort and radish seeds in the preparation of drugs for treating hypertension

A technology of Dendrobium officinale and hypertension is applied in the application field of preparing drugs for treating hypertension, health food and homologous food of medicine and food, which can solve the problems of limited blood pressure lowering effect, achieve stable curative effect, save medicinal materials, and reduce blood pressure. improved effect

Active Publication Date: 2022-01-07
HANGZHOU DANHE PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the limited effect of lowering blood pressure under conventional usage conditions, there are currently no Chinese patent medicines for the treatment of high blood pressure with Polygonatum, Dendrobium officinale leaves or Dendrobium officinale

Method used

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  • Application of Dendrobium officinale leaves, sealwort and radish seeds in the preparation of drugs for treating hypertension
  • Application of Dendrobium officinale leaves, sealwort and radish seeds in the preparation of drugs for treating hypertension
  • Application of Dendrobium officinale leaves, sealwort and radish seeds in the preparation of drugs for treating hypertension

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] 5 copiers of Iron Dendrobium, 5 pieces of Huangjing:

[0040] Take the dried iron dendrobium 300g, take 300g of Huangjing in accordance with the 2015 "Chinese Pharmacopoeia".

[0041] The yellow brine was 10 times, heated and extracted 2 hours, and the water extract was combined and concentrated.

[0042] Grinding the Iron Dendrobium Leaves to the fine powder, and adds the iron dendrobium and fine powder to the Huangjie extract, adding a suitable excipient to the Iron Dendrobium. For Example 1 sample. Oral, adults per day is equivalent to reducing blood pressure 20g (can be small to 5g, can be 30g).

Embodiment 2

[0044] 5 copiers of Iron Dendrobium, 1 yellow, 1 copy:

[0045] Take the dry iron dendrobium 600g, take the 2015 version of "China Pharmacopoeia".

[0046] The yellow brine was 10 times, heated and extracted 2 hours, and the water extract was combined and concentrated.

[0047] Gold the Iron Dendrobium Leaves to the fine powder, into the yellow-absorbent extract, add the fine powder of the iron dendrobium, and add a suitable excipient according to the pharmaceutically conventional addition, and is made into iron dendrobium leaf gums. For Example 2 samples. Oral, adults per day is equivalent to the amount of blood pressure equivalent to 18 g of the blood pressure (5 g of a small to 5g, can be 30 g).

Embodiment 3

[0049] 1 part of the iron dendrobium, 5 pieces of Huangjing:

[0050] Take the dry iron dendrobium 120g, take the 2015 version of "China Pharmacopoeia".

[0051] The yellow brine was 10 times, heated and extracted 2 hours, and the water extract was combined and concentrated.

[0052] Gold the iron leather dendrobium leaves to the fine powder, into the yellow-croping extract, add the fine powder of the iron dendrobium, add suitable excipients according to the pharmaceutically acceptable conventional addition, and make the iron dendrobellipglodium leaf 黄 suspension particles. For Example 3 samples. Oral, adults per day is equivalent to the amount of blood pressure equivalent to 18 g of the blood pressure (5 g of a small to 5g, can be 30 g).

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Abstract

The invention relates to medicine and food preparation technology, and aims to provide the application of dendrobium officinale leaves, sealwort and radish seeds in the preparation of medicines for treating hypertension. Including: take dried leaves of Dendrobium officinale, 1-25 parts of sealwort, or 1-25 parts of raisin seeds, heat water to extract twice, combine the two extracts and then concentrate; grind the leaves of Dendrobium candidum to fine powder, Add to the combined extract; Add excipients according to the conventional pharmaceutical processing method to make various dosage forms of drugs for the treatment of high blood pressure, food and medicine homologous food with the function of treating high blood pressure, or health food with the function of lowering blood pressure . In the present invention, the Polygonatum water extract is used in conjunction with Dendrobium officinale leaves, and its antihypertensive effect is greatly improved. Dendrobium officinale leaves are directly used as medicine after "grinding into fine powder". The utilization of medicinal ingredients is more complete than traditional methods such as water extraction, which is beneficial to the improvement of antihypertensive effect. Combined with radish seed water extract, it can achieve both qi and yin supplements, while promoting qi and lowering qi, nourishing without stagnation, and improving the curative effect.

Description

Technical field [0001] The present invention relates to pharmaceutical and food preparation techniques, particularly directed to leaf Dendrobium, Polygonatum radish seed and for treating hypertension drugs, health foods and drugs in food applications in food homologous. Background technique [0002] Hypertension is a common clinical high incidence, with severe damage to vital organs heart, brain and kidney. Western treatment of hypertension is still a lack of physical adjustment and can adjust blood pressure (antihypertensive) drugs. Antihypertensive therapy modern medicine are symptomatic treatment. The most commonly used antihypertensive agents include calcium channel blockers (CCB), angiotensin converting enzyme inhibitors (ACEI), angiotensin Ⅱ receptor blocker (ARB), five kinds of diuretics and β-blockers , still can not completely prevent the progression of hypertension and its secondary lesions. Most hypertensive patients require two or more kinds of antihypertensive prescr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/00A61K36/8984A61P9/12A23L33/105A23L33/10
Inventor 吴人照吴悦陈璇任泽明
Owner HANGZHOU DANHE PHARM CO LTD
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