Use of tumor markers CA9 and UCA1 in preparation of kit for non-invasive detection of probability of bladder cancer

A tumor marker, non-invasive technology, applied in the field of detection kits, to achieve easy acceptance, reduced inspection frequency, and good specificity

Active Publication Date: 2019-05-17
GUANGZHOU HENGTAI BIOTECH +1
View PDF7 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, domestic patents on exosomes mainly focus on the separation and detection of exosomes, but there are few public reports on the use of exosomes extracted from urine for auxiliary diagnosis of bladder cancer. Only Zhejiang University has published a urine exosome An integrated detection method and detection chip for body separation, enrichment and dete

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Use of tumor markers CA9 and UCA1 in preparation of kit for non-invasive detection of probability of bladder cancer
  • Use of tumor markers CA9 and UCA1 in preparation of kit for non-invasive detection of probability of bladder cancer
  • Use of tumor markers CA9 and UCA1 in preparation of kit for non-invasive detection of probability of bladder cancer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0043] The non-invasive detection method of bladder cancer based on urinary exosomes of the present invention will be described in detail below with reference to the drawings and specific examples.

[0044] From September 2017 to March 2018, the inventor collected urine samples from 176 patients diagnosed with bladder cancer by cystoscopy and pathological diagnosis at Sun Yat-sen University Cancer Center, which was defined as the bladder cancer group. In addition, 123 urine samples were also collected. Urine samples from healthy volunteers were defined as the control group. All sample providers in this study were informed of the purpose of this study and signed informed consent.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses use of tumor markers CA9 and UCA1 in the preparation of a kit for non-invasive detection of a probability of bladder cancer. The use can be used for initial screening and postoperative follow-up of suspected bladder cancer, reduce the frequency of cystoscopy, reduce the pain and risk of a patient, and have important significance for filling the blank of a domestic moleculardiagnosis product of bladder cancer in vitro.

Description

technical field [0001] The invention relates to the field of detection kits, in particular to the application of tumor markers CA9 and UCA1 in the preparation of non-invasive detection kits for bladder cancer probability. Background technique [0002] Bladder cancer refers to the most common malignant tumor of the urinary system that occurs on the bladder mucosa, with an average age of onset of about 65 years, of which about 90% are transitional cell carcinoma, and the other 10% are mainly squamous cell carcinoma and adenocarcinoma. The incidence rate of bladder cancer in the national tumor registration area is 6.61 / 100,000, ranking ninth in the incidence rate of malignant tumors. Due to the obvious characteristics of poor prognosis and easy recurrence, and the 5-year survival rate of bladder cancer patients detected and treated early is greater than 90%, early diagnosis is of great significance for the treatment of this disease. Cystoscopy is currently the most reliable me...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C12Q1/6886C12N15/11
Inventor 李国荣曹艳张淑怡徐建华邓敏刘万里张朋张扬
Owner GUANGZHOU HENGTAI BIOTECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap