Pair of panaxtriol saponins and preparation method of mixture of pair of panaxtriol saponins
A technology of triol saponins and mixtures, applied in the field of medicine, can solve problems such as undiscovered preparation methods and the like
Inactive Publication Date: 2019-05-21
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Problems solved by technology
The invention belongs to the technical field of medicine and relates to a pair of panaxtriol saponins and a preparation method of a mixture of the pair of panaxtriol saponins. The names of a pair of compounds are 20(R)-25-methoxyl-dammarane-3beta,12beta,20-triol (25 Rmdt for short) and 20(S)-25-me-thoxyl-dammarane-3beta,12beta,20-triol (25 Smdt for short). The compounds involved in the invention can be prepared by an acid hydrolyzing method, an alkaline hydrolyzing method and a synthesizing method; and the preparation method is simple and feasible. The 25 Rmdt, the 25 Smdt and the mixture (racemate) of the 25 Rmdt and the 25 Smdt can be prepared into varieties of clinically feasible dosage forms together with pharmaceutically acceptable carriers; it is proved, by researches, that the compounds and preparations of the compounds have an obvious antitumor effect, the compounds can be prepared into any medicinal and health care product dosage form for treating different cancers, and the compounds are mainly applied to prevention and treatment of malignant tumors and have a wide application prospect.
Organic active ingredientsSteroids +1
ChemistryDosage form +3
- Experimental program(1)
Description & Claims & Application Information
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