Neural photoelectrode and preparation method thereof

Abstract

The invention discloses a neural photoelectrode and a preparation method thereof, and belongs to the field of preparation of neural photoelectrodes. The neural photoelectrode comprises a sapphire light array device, a wire electrode and ultraviolet glue. The wire electrode is fixed to the surface of the sapphire light array device through the ultraviolet glue. The sapphire light array is attachedto the wire electrode to isolate a stimulation channel and a recording channel in a spatial range, and effectively reduce electrical stimulation noise. The neural photoelectrode is convenient to assemble, and the position and the quantity of the wire electrode can be determined according to the requirements. The light array mode adopted by a light source facilitates stimulation and recording of multiple brain regions, and achieves high-throughput detection of neural activity.

Description

technical field

[0001] The invention relates to the field of nerve photoelectrode preparation, in particular to a nerve photoelectrode and a preparation method thereof. Background technique

[0002] The brain is the system with the most complex structure and function in the living body. It is composed of hundreds of billions of nerve cells. These cells rely on two modes of pulse discharge and neurotransmitter release to complete various complex information transmission and integration functions. Comprehensive, accurate, real-time, and synchronous detection of these multi-dimensional information is a basic means and an important way to promote the detection, diagnosis, and rehabilitation of major neurological diseases. Electrodes traditionally used to monitor brain neural activity use electrical stimulation to stimulate and record neurons. This method is not selective for neurons and will cause irreversible damage to cells. Therefore, people use a combination of optical techn...

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