Liquid transfer device for automatic sample preparation system and application of liquid transfer device
A technology of a pipetting device and a preparation system, which is applied to analysis materials, instruments, etc., can solve problems such as restricting the popularization and application of automated sample preparation systems, affecting the wide application of gene sequencing technology, and large volume of the pipetting device, avoiding manual operation. Potential errors, improved sample preparation efficiency, easy maintenance results
Pending Publication Date: 2019-06-07
MGI TECH CO LTD
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Problems solved by technology
[0005] On the one hand, the existing automated sample preparation system and its pipetting device are monopolized by foreign countries; on the other hand, the pipetting device is large in size, high in cost, and difficult to maintain
This greatly restricts the promotion and application of automated sample preparation systems, which in turn affects the wide application of gene sequencing technology in clinical laboratory testing.
Method used
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Embodiment
[0039] This example is used in pipetting devices for automated sample preparation systems such as figure 1 and figure 2 As shown, it includes a bottom plate 1 and a pipetting module 2 and a stripping module 3 installed on the bottom plate 1 . Wherein, the pipetting module 2 includes a multi-channel plunger pump 21 and a plunger pump driving device 22; as image 3 As shown, the plunger pump 21 is composed of a sealed cavity 211 and a plunger 212 embedded in the sealed cavity 211, image 3 The right picture in the middle is the internal sectional view of part A. It can be seen that the plunger 212 is embedded in the sealing cavity 211; one end of the sealing cavity 211 is inserted into the plunger 212, and the other end is detachably connected with the gun tip adapter 4, and the gun tip adapter 4 is directly Connected to the sealed cavity 211; each channel has an independent sealed cavity and plunger, and is connected to a gun tip adapter 4; the head of the plunger 212 is ins...
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The invention discloses a liquid transfer device for an automatic sample preparation system and application of the liquid transfer device. The liquid transfer device comprises a base plate and a liquid transfer module and a stripper module mounted in the base plate; the liquid transfer module comprises a multi-channel plunger pump and a driver thereof; the plunger pump is composed of a sealed cavity and a plunger embedded in the cavity; one end of the sealed cavity is plugged with plungers, and the other end of the cavity is connected with a gun head adapter; the tail end of each plunger is connected to a plunger connecting slide block; the driver of the plunger pump is mounted on the base plate, and a moving end of the driver is connected to the plunger connecting slide block; the stripper module comprises a stripper plate and a driver thereof, the stripper plate is provided with a through hole adapted to the gun head adapter, and the adapter is connected with a gun head by penetrating the through hole; and the driver of the stripper plate is mounted on the base plate, and a movable end of the driver of the stripper plate is connected to the stripper plate. The liquid transfer unit is simple in structure, unlikely to damage the gun head, easy to maintain, high in automatic degree and capable of replacing manual or semi-automatic work at present, and thus, provides basis for automatic sample preparation in clinical experiments, scientific research institutions and quarantine systems.
Description
technical field [0001] The present application relates to the field of automatic sample preparation systems, in particular to a pipetting device for automatic sample preparation systems and its application. Background technique [0002] At present, there is no highly automated solution for automated sample preparation before next-generation sequencing in China, and multiple instruments are usually required to complete the entire sample preparation process. With the development and wide application of gene sequencing technology, gene sequencing has gradually become an important basis and means for clinical laboratory testing. [0003] Therefore, a complete low-throughput automated sample preparation system suitable for clinical laboratory testing has important application value for gene sequencing in hospitals. [0004] The core component of the automated sample preparation system is the pipetting device. The function of the pipetting device is to perform accurate, efficient...
Claims
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Inventor 高建东李景吴文昊邹良英刘健
Owner MGI TECH CO LTD