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Systems and methods for estimating the risk of a future hypoglycemic event

A technology of events and risks, applied in applications, drug devices, drugs or prescriptions, etc., can solve problems such as negative patients

Pending Publication Date: 2019-06-07
NOVO NORDISK AS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to concerns that patients tend to underestimate the size of feeding boluses, which lead to non-adherence to treatment and hyperglycemia, which have negative long-term consequences on patient health

Method used

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  • Systems and methods for estimating the risk of a future hypoglycemic event
  • Systems and methods for estimating the risk of a future hypoglycemic event
  • Systems and methods for estimating the risk of a future hypoglycemic event

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0117] The present disclosure relies on obtaining first and second data sets. The first data set includes: a plurality of insulin medication records taken over the course of time. Each corresponding insulin medication record of the plurality of medication records includes (i) a corresponding insulin medication injection event comprising injection into the subject using the corresponding insulin injection device or an insulin injection device of one or more insulin injection devices The amount of insulin drug in the body, (ii) the corresponding electronic injection event timestamp over the course of time, which was automatically generated by the corresponding insulin injection device when the corresponding insulin drug injection event occurred, and (iii) from one or more types of One of the insulin medications is the corresponding type of insulin medication injected into the subject. The second data set includes a plurality of autonomic glucose measurements for the subject, an...

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Abstract

A device (250) for estimating the risk of a future hypoglycemic event for a subject with a standing insulin regimen (206), wherein the standing insulin regimen comprises one or more types of insulin medicament dosage regimen (208), wherein each of the one or more types of insulin medicament dosage regimen (208) comprises a type of insulin medicament (210) defining one or more types of insulin medicaments. Using the evaluation of a glucose concentration, a first time derivative and an insulin on board for the subject in a current metabolic state, and the evaluation of a glucose concentration, afirst derivative and a historical insulin on board to estimate a hypoglycemic risk measure.

Description

technical field [0001] The present disclosure generally relates to systems, methods, and computer programs for estimating the risk of future hypoglycemic events in a subject utilizing a standing insulin regimen, wherein the standing insulin regimen includes: utilizing one or more types of insulin medications such that the subject Insulin drug dosing regimens that minimize the risk of experiencing hypoglycemia risk. Background technique [0002] Traditional insulin drug delivery systems have involved the use of pump systems that deliver frequent recurring doses of insulin drug. Insulin pumps use only one type of insulin, short-acting pump insulin, which simulates basal and prandial insulin secretion by utilizing different pump rates during the day. Additional types of delivery systems have been developed, such as insulin pens, which can be used to self-administer insulin drug regimens in the form of less frequent insulin drug injections. A common approach to type 1 and type...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16H50/70
CPCG16H50/70G16H10/60G16H50/30G16H50/20G16H20/10A61B5/14532A61B5/4839A61B5/7275A61B5/746A61M5/1723A61M2205/52
Inventor B.W.范奥登T.B.阿拉多蒂尔P.布洛克梅尔H.本特森
Owner NOVO NORDISK AS
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