Preparation method of hydroxypropyl methyl cellulose ether with high gelation temperature
A technology of hydroxypropyl methylcellulose and high gel, which is applied in the field of preparation of hydroxypropyl methylcellulose ether, can solve problems such as product instability, low gel temperature, and poor product uniformity, and achieve the goal of reaction process The effect of short time consumption, good uniformity and mild reaction conditions
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Embodiment 1
[0027] The invention discloses a preparation method of hydroxypropyl methyl cellulose ether with high gel temperature, and the specific steps are as follows:
[0028] (1) Alkalization
[0029] adding cellulose powder into the alkalization kettle for alkalization;
[0030] (2), etherification
[0031] First heat up reaction and then low temperature reaction, carry out two-step etherification;
[0032] (3), adjust acid
[0033] Neutralization and regulation to achieve acid regulation;
[0034] (4), post-processing
[0035] After pulverization, add a crosslinking modifier of 3% by weight of cellulose powder to the system, and stir for 15 minutes at a temperature of 60°C.
[0036] In the step (1), the cellulose powder is wood pulp powder.
[0037] In the step (2), the temperature of the heating reaction is 80°C, the reaction time is 2h, and the first step of etherification is performed, and then the temperature of the low temperature reaction is 50°C, and the reaction time i...
Embodiment 2
[0044] The invention discloses a preparation method of hydroxypropyl methyl cellulose ether with high gel temperature, and the specific steps are as follows:
[0045] (1) Alkalization
[0046] adding cellulose powder into the alkalization kettle for alkalization;
[0047] (2), etherification
[0048] First heat up reaction and then low temperature reaction, carry out two-step etherification;
[0049] (3), adjust acid
[0050] Neutralization and regulation to achieve acid regulation;
[0051] (4), post-processing
[0052] After pulverization, add a crosslinking modifier of 2% by weight of cellulose powder to the system, and stir for 30 minutes at a temperature of 55°C.
[0053] In the step (1), the cellulose powder is wood pulp powder.
[0054] In the step (2), the temperature of the heating reaction is 90°C, the reaction time is 2.5h, the first step etherification is performed, and then the temperature of the low temperature reaction is 40°C, and the reaction time is 3.5...
Embodiment 3
[0061] The invention discloses a preparation method of hydroxypropyl methyl cellulose ether with high gel temperature, and the specific steps are as follows:
[0062] (1) Alkalization
[0063] adding cellulose powder into the alkalization kettle for alkalization;
[0064] (2), etherification
[0065] First heat up reaction and then low temperature reaction, carry out two-step etherification;
[0066] (3), adjust acid
[0067] Neutralization and regulation to achieve acid regulation;
[0068] (4), post-processing
[0069] After crushing, add 4.0% by weight of cellulose powder crosslinking modifier to the system, and stir for 30 minutes at a temperature of 50-70 °C.
[0070] In the step (1), the cellulose powder is wood pulp powder.
[0071] In the step (2), the temperature of the heating reaction is 70°C and the reaction time is 2h, the first step of etherification is performed, and then the temperature of the low temperature reaction is 60°C and the reaction time is 4h, ...
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