UV (ultraviolet lamp ionization source)-FAIMS (high-field asymmetric waveform ion mobility spectrometry)-based quantitative detection method for volatile organic compound

Abstract

The invention relates to an UV (ultraviolet lamp ionization source)-FAIMS (high-field asymmetric waveform ion mobility spectrometry)-based quantitative detection method for volatile organic compound and belongs to the technical field of analysis and detection. According to the method, a flow velocity is changed, current signals are detected, and a standard product flow velocity-signal strength relation curve under a fixed concentration is obtained; a saturation flow velocity value corresponding to saturation signal strength is obtained according to the relation curve, and the small flow velocity region of the curve is intercepted, an ion composite loss coefficient is solved according to an ion composite equation; under a condition that a carrier gas flow velocity is larger than the saturation flow velocity, FAIMS analysis is carried out, so that a separation voltage-peak height relation curve is obtained, and the concentration mean value of a plurality of sets of samples is solved according to a quantitative model, so that quantitative analysis of a to-be-detected substance is realized. The quantitative detection method provides important reference for the ion mobility theory in the high-field asymmetric waveform ion mobility spectrometry and provides an important basis for promoting the expansion of the ion mobility spectrometry technology to more extensive quantitative analysis fields from qualitative analysis fields such as safety early warning and the like.

Description

technical field [0001] The invention relates to a quantitative detection method of volatile organic compounds, more specifically to a UV-FAIMS (ultraviolet lamp ionization source-high field asymmetric waveform ion mobility spectrometry) quantitative detection method of volatile organic compounds, belonging to the technical field of analysis and detection . Background technique [0002] Ion mobility spectrometry is a material composition detection technology based on the physical characteristics of ion mobility. It has a series of advantages such as high sensitivity, fast speed, and normal pressure work. mainstream technology. There are hundreds of thousands of desktop and portable ion mobility spectrometers operating in airports, customs, borders and other sensitive areas around the world, providing a reliable detection technology guarantee for public safety early warning. There are many kinds of ion mobility spectrometry, including time-of-flight ion mobility spectrometry...

AI Technical Summary

Problems solved by technology

[0004] However, in areas such as environmental monitoring and food safety testing, which also urgently need on-site detection methods, ion mobility spectrometry is rarely seen.

The key obstacle lies in the lack of research on ion transport process and the locality of data acquisition, resulting in the lack of reliable quantitative detection methods for high-field asymmetric waveform ion mobility spectrometry, and its material composition detection method is largely "qualitative discovery". ” instead of “quantitative analysis”

This greatly limits the scope of application of ion mobility spectrometry, an on-site detection technique.

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