Multi-dimensional liquid chromatography separation system based on two-position eight-way valve

A multi-dimensional liquid chromatography and separation system technology, applied in the direction of material separation, analysis materials, measuring devices, etc., can solve the problem of limited separation capacity and achieve low-cost effects

Inactive Publication Date: 2019-08-23
李宜珊
View PDF2 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The serial mode multidimensional liquid chromatography system is represented by the sepbox series products of the fully automatic high-throughput preparative separation system of Sepiatec GmbH in Germany, but this product can only perform two-dimensional chromatographic separation, and the separation capacity is limited

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Multi-dimensional liquid chromatography separation system based on two-position eight-way valve
  • Multi-dimensional liquid chromatography separation system based on two-position eight-way valve
  • Multi-dimensional liquid chromatography separation system based on two-position eight-way valve

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0036] Embodiment: A kind of structure of multidimensional liquid chromatography separation system

[0037] In this embodiment, the enrichment column array B has 9 enrichment columns, which are sequentially numbered as the first enrichment column of the enrichment column array B, the second enrichment column, etc., and the last number is the column of the enrichment column array B. The ninth enrichment column; the enrichment column array A is a two-stage enrichment column array, and each enrichment column array has 9 enrichment columns, that is, the enrichment column array A has 18 enrichment columns, and the numbers are enrichment The first enrichment column of column array A, the second enrichment column, etc., the last number is the 18th enrichment column of enrichment column array A; the liquid chromatography separation column array has 5 separation columns, which are numbered sequentially The first separation column, the second separation column, etc., the last one is the...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides a multi-dimensional liquid chromatography separation system comprising a high performance liquid chromatography gradient pump A, a high performance liquid chromatography gradient pump B, a high performance liquid phase dilution liquid pump, a gradient mixer A, a gradient mixer B, a sampling valve, an enriched column array A, an enriched column array B, a distillate collector, a liquid chromatography column array, a detector, a two-position eight-way valve and a connecting pipeline. Conversion from the previous dimensional separation state to the next dimensional separation state is realized by the two-position eight-way valve to achieve three or more-dimensional chromatographic separation. Through the liquid chromatography separation column array, each-dimensional chromatographic separation column is selected, thereby, based on the same gradient elution system and the same detector, realizing the all on-line monitoring and control of multi-dimensional chromatographic separation and realizing controllable degree of cleanliness of the enrichment columns and separation columns. Each-dimensional separation is connected by an enrichment column and a diluent pump is used to assist in compound enrichment or capture. The multi-dimensional liquid chromatography separation system provided by the invention achieves efficient separation of monomer compounds in complex system samples with high separation difficulty by selecting different combinations of chromatographic stationary phases and mobile phases.

Description

technical field [0001] The invention belongs to the technical field of high performance liquid chromatography separation, and relates to a multidimensional liquid chromatography separation system. Background technique [0002] With the development of separation technology, exploring and separating components in complex sample systems has become a hot research field. Multidimensional liquid chromatography technology can effectively improve the resolution of complex sample component separation by increasing peak capacity, and has become the development direction of fast chromatography separation technology. Multidimensional liquid chromatography technology is a liquid chromatography technology that sequentially injects the eluent of the first-dimensional chromatographic column of the sample into the subsequent dimensional chromatographic column for further separation. This separation technology can utilize two or more chromatographic columns with different separation mechanis...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/06G01N30/08G01N30/60
CPCG01N30/06G01N30/08G01N30/60
Inventor 李宜珊
Owner 李宜珊
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap