Long-acting skin marking pen based on genipin coloring principle

Abstract

The invention discloses a long-acting skin marking pen based on a genipin coloring principle. The long-acting skin marking pen comprises raw materials as follows: 1%-6% of genipin, 1%-3% of gentian violet, 20%-30% of ethyl alcohol, 10%-20% of propylene glycol, 0.3%-0.5% of xanthan gum, 2%-3% of polyvinylpyrrolidone and 60%-70% of water. The genipin is added, is an iridoid compound and can react with silk fibroin to form a final color product, the color product can permanently dye hard membrane outer layers of human skin to form black blue temporary tattoo unit skin is regenerated after 2-3 weeks, so that the duration is up to 2-3 weeks after coloring by the skin marking pen, a traditional invasive laser dotting making manner can be replaced, pain experience of patients during marking can be avoided; secondly, the long-acting skin marking pen can avoid the condition that colors fade after marking by common skin marking pens to affect treatment accuracy.

Description

technical field [0001] The invention relates to the related field of ink technology, in particular to a long-lasting skin marker pen based on the genipin coloring principle. Background technique [0002] The role and status of radiotherapy in tumor treatment has become increasingly prominent, and it has become one of the main means of treating malignant tumors. About 70% of cancer patients require radiation therapy as part of their cancer treatment. In order to ensure the repeatability of each radiotherapy position, it is necessary to accurately mark the radiotherapy positioning line on the patient's body surface for laser alignment during each treatment, that is, radiotherapy marking. Currently, the commonly used body surface marking methods include laser dots and ordinary skin markers. and ordinary oil-based pen markers. [0003] The commonly used body surface marking methods have the following disadvantages: [0004] (1) Laser spotting: refers to using a laser beam to ...

AI Technical Summary

Problems solved by technology

[0004] (1) Laser spotting: refers to using a laser beam to permanently mark the patient's skin surface, and laser marking is an invasive mark that causes unbearable pain to the patient. At the same time, laser spotting may cause permanent scars and affect the appearance;

[0005] (2) Ordinary skin markers: Currently commonly used skin markers mainly use gentian violet solution as ink, but ordinary skin markers are easy to fade after marking, and the marking duration is short (about 3-5 days), but due to bathing , body rubbing, clothing friction and many other factors often cause radiotherapy marks to be blurred or even completely lost;

[0006] (3) Ordinary oil-based pens: The ordinary oil-based marker pens currently used are easy to fade after marking the skin, and the coloring time is short (about 2-3 days), and the ink of ordinary oil-based pens is very irritating to human skin.

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