HA collagen stock solution and preparation method thereof

A collagen and stock solution technology, used in pharmaceutical formulations, cosmetic preparations, cosmetic preparations, etc., to achieve the effects of lightening wrinkles, promoting cell activation and growth, and anti-inflammatory skin maintenance.

Inactive Publication Date: 2019-09-13
广州芊舟生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In view of the fact that there is still no product on the market that is effective in anti-aging, anti-wrinkle, and maintaining skin elasticity and is affordable, therefore, the development of a HA collagen stock solution will have broad market prospects

Method used

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  • HA collagen stock solution and preparation method thereof
  • HA collagen stock solution and preparation method thereof
  • HA collagen stock solution and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028]Composition of raw materials (parts by weight): 0.2 parts of trisodium ethylenediamine disuccinate, 0.3 parts of ascorbyl palmitate, 1 part of hyaluronic acid modified collagen, 2 parts of aspartic acid, 1.5 parts of D-pantothenic acid, allantoic acid 1 part of vegetable, 2 parts of euglena, 1 part of calendula extract, 2 parts of polyethylene wax, 3 parts of carbomer, 1 part of citronella oil, 0.02 part of benzotriazole and 50 parts of water.

[0029] Hyaluronic acid-modified collagen is prepared by the following method: weigh 2g of collagen in a beaker, add ultrapure water to prepare a 2g / 100mL collagen solution, dissolve in a water bath at 50°C for 30min, and filter with suction to obtain a pure collagen solution , add 10g of glycerin, mix well, add a hyaluronic acid solution with a mass concentration of 0.5g / 100mL at a volume fraction of 10%, heat and stir at 70°C for 30min, and centrifuge at a low speed of 2000r / min for 4min to obtain a modified hyaluronic acid Coll...

Embodiment 2

[0036] Composition of raw materials (parts by weight): 0.5 parts of trisodium ethylenediamine disuccinate, 0.5 parts of ascorbyl palmitate, 3 parts of hyaluronic acid modified collagen, 5 parts of arginine, 3.5 parts of D-pantothenic acid, allantoin 2 parts, 4 parts of Euglena, 3 parts of calendula extract, 5 parts of polyethylene wax, 5 parts of carbomer, 2 parts of citronella oil, 0.05 parts of benzotriazole and 100 parts of water.

[0037] Hyaluronic acid-modified collagen is prepared by the following method: weigh 2g of collagen in a beaker, add ultrapure water to prepare a 2g / 100mL collagen solution, dissolve in a water bath at 50°C for 30min, and filter with suction to obtain a pure collagen solution , add 10g of glycerin, mix well, add a hyaluronic acid solution with a mass concentration of 0.5g / 100mL at a volume fraction of 10%, heat and stir at 70°C for 30min, and centrifuge at a low speed of 2000r / min for 4min to obtain a modified hyaluronic acid Collagen.

[0038] ...

Embodiment 3

[0044] Composition of raw materials (parts by weight): 0.3 parts of trisodium ethylenediamine disuccinate, 0.35 parts of ascorbyl palmitate, 1 part of hyaluronic acid modified collagen, 1 part of glycine, 2 parts of alanine, 1.7 parts of D-pantothenic acid , 1.2 parts of allantoin, 2 parts of euglena, 1 part of calendula extract, 3 parts of polyethylene wax, 3 parts of carbomer, 1.2 parts of citronella oil, 0.03 parts of benzotriazole and 60 parts of water.

[0045] Hyaluronic acid-modified collagen is prepared by the following method: weigh 2g of collagen in a beaker, add ultrapure water to prepare a 2g / 100mL collagen solution, dissolve in a water bath at 50°C for 30min, and filter with suction to obtain a pure collagen solution , add 10g of glycerin, mix well, add a hyaluronic acid solution with a mass concentration of 0.5g / 100mL at a volume fraction of 10%, heat and stir at 70°C for 30min, and centrifuge at a low speed of 2000r / min for 4min to obtain a modified hyaluronic ac...

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Abstract

The invention provides an HA collagen stock solution. The HA collagen stock solution is prepared from raw materials in parts by weight as follows: 0.2-0.5 part of trisodium ethylenediamine disuccinate, 0.3-0.5 part of ascorbyl palmitate, 1-3 parts of hyaluronic acid modified collagen, 2-5 parts of amino acid, 1.5-3.5 parts of D-pantothenic acid, 1-2 parts of allantoin, 2-4 parts of euglena polysaccharides, 1-3 parts of a calendula extract, 2-5 parts of polyethylene wax, 3-5 parts of carbomer, 1-2 parts of citronella oil, 0.02-0.05 part of benzotriazole and 50-100 parts of water. The repair cream is simple to prepare, the raw materials are widely sourced, hyaluronic acid modified collagen is used as a core component, first conditioning and late nourishing and foundation strengthening are realized, the collagen component of skin is supplemented, skin vitality is repaired, damaged skin base is mainly repaired, the generation of skin is improved, nutrients are poured, fundamental beauty change is brought, and the HA collagen stock solution has broad application prospects.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to a HA collagen stock solution and a preparation method thereof. Background technique [0002] Factors that generally affect the appearance of facial skin include: spots, acne, wrinkles, dullness, enlarged pores, dryness and other issues. The skin of humans and higher animals consists of three layers: epidermis, dermis (mesoderm), and subcutaneous tissue. Collagen accounts for 72% of the skin, and 80% of the dermis is collagen. The dermis of the skin is mainly composed of collagen fibers and elastic fibers, which provide the most basic support. The collagen fibers in young skin are dense and thick, so the elasticity is very high. it is good. With age, collagen will gradually lose. When women are 20 years old, collagen has already begun to age and lose, and its content decreases year by year. At 25 years old, it enters the peak period of loss. At 40 years old, the content is le...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/42A61K8/49A61K8/65A61K8/67A61K8/73A61K8/81A61K8/92A61Q17/04A61Q19/00A61Q19/08C08B37/08C08H1/00
CPCA61K8/42A61K8/4946A61K8/496A61K8/65A61K8/676A61K8/73A61K8/732A61K8/735A61K8/8147A61K8/922A61K2800/56A61Q17/04A61Q19/00A61Q19/008A61Q19/08A61K8/9789C08B37/0072C08H1/00
Inventor 何敬忠
Owner 广州芊舟生物科技有限公司
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