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Isolation membrane capable of reactivating endometrium basal layer in uterine cavity and preparation method thereof

A technology of isolation membrane and uterine cavity, which is applied in the field of isolation membrane with the function of reactivating the endometrium basal layer in the uterine cavity and its preparation field, which can solve the problems of inability to effectively prevent postoperative adhesions and achieve the effect of preventing uterine adhesions

Active Publication Date: 2022-06-17
YIPURUN SHANGHAI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] In order to solve the problem that the above-mentioned prior art cannot effectively prevent postoperative adhesions, the present invention aims to provide a barrier membrane capable of reactivating the endometrial basal layer in the uterine cavity and a preparation method thereof

Method used

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  • Isolation membrane capable of reactivating endometrium basal layer in uterine cavity and preparation method thereof
  • Isolation membrane capable of reactivating endometrium basal layer in uterine cavity and preparation method thereof
  • Isolation membrane capable of reactivating endometrium basal layer in uterine cavity and preparation method thereof

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Embodiment Construction

[0051] Below in conjunction with the accompanying drawings, preferred embodiments of the present invention are given and described in detail.

[0052] like figure 1 As shown, according to a preferred embodiment of the present invention, the isolation membrane 1a with the function of reactivating the endometrium basal layer in the uterine cavity is in the shape of an inverted trapezoid. mouth location. It should be understood that, in the deployed state after implantation, the shape of the isolation membrane 1a is selected to suit the physiological shape and size of the uterus to isolate the anterior and posterior walls of the uterus as fully as possible, thereby separating the anterior and posterior walls of the uterus. exposure to a minimum. When the isolation membrane 1a is implanted, the doctor only needs to put the sheet into the uterus with the assistance of conventional instruments. It should be understood that the doctor can also curl the sheet-like device into a cyl...

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Abstract

The invention relates to an isolation membrane capable of reactivating the endometrial basal layer in the uterine cavity, comprising a degradable base material and medicine, wherein the medicine is uniformly dispersed in the degradable base material, and the medicine includes at least one estrogen. The present invention also provides a method for preparing an isolation membrane capable of reactivating the function of the endometrial basal layer in the uterine cavity, comprising dissolving the degradable base material in a solvent, adding at least one estrogen-containing drug to form a mixed solution or a uniform Dispersion, and then static or cast film. In the present invention, by loading estrogen on the degradable base material, after the surgical trauma occurs, the uterine wound is isolated through the isolation membrane, and the basal layer of the endometrium is continuously activated by drug stimulation in the same period, so that the basal layer can regenerate the functional layer. Moreover, after the isolation membrane is degraded, the normal endometrial structure is restored, so as to prevent uterine adhesions after surgical trauma.

Description

technical field [0001] The invention relates to a medical device used in the uterus of women, and more particularly relates to an isolation membrane with the function of reactivating the basal layer of the endometrium in the uterine cavity and a preparation method thereof. Background technique [0002] The uterus is the organ that produces menstruation and conceives the fetus. It is located in the center of the pelvic cavity and is unique to women. The size of the uterus is related to age and fertility. The nulliparous is about 7.5cm long, 5cm wide and 3cm thick. The uterus can be divided into three parts: the bottom, the body and the neck. The uterine cavity is an inverted triangle with a depth of about 6cm, and the upper two corners are "uterine horns" leading to the fallopian tubes. The lower end is narrow as the "isthmus", about 1cm long. [0003] Miscarriage, ring placement, surgery and other uterine cavity operations, as well as infection and other reasons can cause ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L31/04A61L31/06A61L31/14A61L31/16
CPCA61L31/045A61L31/047A61L31/06A61L31/042A61L31/16A61L31/148A61L2300/43
Inventor 魏征杨瑞吴慧玲谢建
Owner YIPURUN SHANGHAI BIOTECH CO LTD