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Chip reaction device-based water quality multi-parameter detection equipment and detection method

A technology of detection equipment and reaction device, which is applied in the field of microchips, can solve the problems of difficult realization, poor fluid controllability, and high machining precision requirements, and achieve the effects of saving chip volume, simplifying chip structure, and low cost

Pending Publication Date: 2019-11-19
CHINA PETROLEUM & CHEM CORP +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] However, there are certain problems when the above-mentioned technologies are applied to on-site detection.
External mechanical pressure drive and electroosmosis drive often need to provide corresponding auxiliary equipment, which violates the requirements of portability and miniaturization of the equipment; although the micropump drive is small in size, it requires high machining accuracy, is difficult to implement, and the technology is not mature enough; Gravity drive does not require external power, but the controllability of fluid is poor, and it is not suitable for small-scale channels (surface tension is stronger than gravity)

Method used

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  • Chip reaction device-based water quality multi-parameter detection equipment and detection method
  • Chip reaction device-based water quality multi-parameter detection equipment and detection method
  • Chip reaction device-based water quality multi-parameter detection equipment and detection method

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Experimental program
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Effect test

Embodiment 1

[0074] The water quality multi-parameter detection equipment of the present invention includes such as figure 1 The chip reaction device shown, the chip reaction device includes a manual sampler 1 and a chip 2;

[0075] figure 1 Middle g shows the structure of the chip 2, the chip 2 is a circular scattering multi-channel chip, including 1 sample inlet 23 and 6 reaction pools 22 equidistant from the sample inlet 23, 6 flow channels Road 21 communicates with each reaction pool 22 and sample inlet 23 respectively; figure 1 In a-d, only the sample inlet 23 of the chip 2 is shown, and in e-f, only a group of flow channels 21 and the reaction pool 22 of the chip 2 are shown;

[0076] Described manual sample injector 1 comprises the cylindrical sample cuvette 12 of polyethylene system, cup-shaped control part 11 and sample discharge part 13, and described control part 11 is arranged on the inside of described sample cuvette 12, and described The sample pool 12 is detachably sealed...

Embodiment 2

[0080] The water quality multi-parameter detection equipment of the present invention includes such as figure 2 The chip reaction device shown, the chip reaction device includes a manual sampler 1 and a chip 2;

[0081] The structure of the chip 2 is the same as in Embodiment 1, figure 2 h shows the structure of chip 2, d-e shows only the sample inlet 23 of chip 2, f-g shows only a group of flow channels 21 and reaction pool 22 of chip 2, a-c shows manual sample injection The sample loading process of device 1;

[0082] Described manual sample injector 1 comprises the tubular sample cell 12 of polyethylene system, the cylindrical control part 11 that is connected with it and sample outlet 13, and described control part 11 is connected with the top of described sample cell 12, uses In order to make the sample enter and hold in the sample cell 12 or to push the sample out of the sample cell 12 through the sample outlet part 13, the control part includes a flexible side wall ...

Embodiment 3

[0086] The water quality multi-parameter detection equipment of the present invention includes such as image 3 The chip reaction device shown, the chip reaction device includes a manual sampler 1 and a chip 2;

[0087] image 3 Middle h shows the structure of the chip 2, the chip 2 is a parallel multi-channel rectangular chip, including three groups of five reaction pools 22 connected in series through the flow channels 21, and each group of reaction pools passes through the flow channels 21 and enters the The sample port 23 is connected; image 3 In d-e, only the sample inlet 23 of the chip 2 is shown, in f-g, only a set of flow channels 21 and the reaction pool 22 of the chip 2 are shown, and in a-c, the sample loading process of the manual injector 1 is shown;

[0088] The manual sample injector 1 comprises a cylindrical sample pool 12 made of polyethylene, a cylindrical control part 11 connected with a piston, and a sample outlet 13, and the control part 11 is connected...

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Abstract

The invention relates to the field of microchips, and discloses chip reaction device-based water quality multi-parameter detection equipment and detection method and application thereof. The water quality multi-parameter detection equipment comprises a chip reaction device, wherein the chip reaction device comprises a manual sampler and a chip, the chip comprises a runner, a reaction pool and a sampling hole, the reaction pool communicates with the sampling hole by the runner, the manual sampler comprises a sample pool, a control part and a sample outlet part, the control part is connected with the sample pool and is used for allowing the sample to enter and maintaining the sample in the sample pool or allowing the sample to be pushed out of the sample pool by the sample outlet part, the sample outlet part is arranged at a side, opposite to the control part, of the sample pool, and the manual sampler is hermetically connected with the sampling hole of the chip. By the water quality multi-parameter detection equipment, a sample flowing mode can be accurately controlled, various functions of sampling, mixing and driving can be achieved manually, the device is simplified, and the operation controllability and repeatability are conveniently provided.

Description

technical field [0001] The invention relates to the field of microchips, in particular to a water quality multi-parameter detection device and detection method based on a chip reaction device and an application thereof. Background technique [0002] One of the development directions of modern instruments is miniaturization, integration and portability. No matter in the field of life science, chemical engineering, or environmental protection, the emergence of micro total analysis system (microTAS) has brought about revolutionary changes. The purpose of micro-total analysis is to integrate functions, integrating complex functions such as sample preparation, separation, purification, reaction, and monitoring that originally needed to be realized in the laboratory into micro-analysis equipment or even credit card-sized chips, so it is also called " Lab on a Chip". [0003] Micro-total analysis technology was proposed by Manz in the 1990s. Thanks to the development of micro-ele...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/01B01J19/00
CPCG01N21/01B01J19/0093
Inventor 姜慧芸孙冰朱红伟姜杰赵磊石宁
Owner CHINA PETROLEUM & CHEM CORP
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