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Method of scanning and assessing lung and vascular health

A health status, vascular technology, applied in the field of medical imaging, can solve the problems of difficult detection of vasculature, no method of obtaining visualization of vasculature, inhibition of pulmonary medical progress, etc.

Inactive Publication Date: 2019-12-06
4DMEDICAL LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In other words, the ability to directly evaluate the efficacy of novel and promising PAH drugs is severely limited by limited data interpretation of clinical trial efficacy
[0014] Despite advances in non-invasive methods such as X-ray computed tomography (CT) in the fields of neurology, cardiology, and oncology, pulmonary medicine has become increasingly difficult due to the difficulty of obtaining clearly visible images of the vasculature. progress is inhibited
While medical contrast agents can improve visibility, they cannot be used when scanning some patients
Furthermore, changes in the vasculature caused by disease states or other conditions remain difficult to detect regardless of the presence of contrast agents
For example, there is currently no method to obtain visualization of the vasculature affected by PAH

Method used

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  • Method of scanning and assessing lung and vascular health
  • Method of scanning and assessing lung and vascular health
  • Method of scanning and assessing lung and vascular health

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Embodiment Construction

[0105] Figure 1 to Figure 3 Three different aspects of implementing the invention are shown. first reference figure 1 , there is a method of scanning for vascular diseases, such as pulmonary hypertension or elevated pulmonary arterial pressure, from three-dimensional in vivo images acquired in the absence of a contrast agent. Blood vessel position data 120 and blood vessel size data 121 are extracted from the three-dimensional image 110 . Once the blood vessel location data 120 and the blood vessel size data 121 are extracted, a region 130 is selected in the extracted blood vessel location data 120 for analysis. The size data 121 in the selected area 130 is then compared with the size data in the corresponding area of ​​the standard data. By performing this comparison, it is possible to determine whether a vessel, such as a pulmonary artery, is in a healthy range (ie, closely matches the standard data set) or in an unhealthy range (ie, deviates significantly from the stand...

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Abstract

The invention relates to a method of scanning for vascular ill health using a data set from an in vivo scan, the method including the steps of: (1) extracting blood vessel location data and blood vessel size data from the scan data set; (2) selecting a region in the extracted vessel location data; and (3) comparing the size data in the selected region to size data in a corresponding region of a normative data set to determine vascular health.

Description

[0001] introduction [0002] This invention was made with Government support under Grant No. HL125806 awarded by the National Institutes of Health. The government has certain rights in this invention. technical field [0003] The invention relates to the field of medical imaging without the use of contrast agents. [0004] In one form, the invention relates to the field of imaging blood vessels, particularly blood vessels such as the pulmonary vasculature. [0005] In a particular aspect, the invention is applicable as a technique for assessing lung and vascular health. [0006] In the following the invention is described with respect to detecting abnormalities in the pulmonary vasculature associated with pulmonary arterial hypertension (PAH) or pulmonary embolism (PE). However, it should be understood that the present invention is not limited thereto and may be applied to detect other irregularities of the vasculature in other parts of the body, such as the brain, heart, l...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00
CPCA61B5/489A61B5/02007A61B5/055A61B5/08A61B5/1075G16H30/40G16H50/20G16H20/10G06T7/0014G06T2207/10081G06T2207/20021G06T2207/20076G06T2207/30101A61B5/0205
Inventor 查铭达·拉吉夫·萨马拉格安德里亚斯·富拉斯希瑟·琼斯维克托·塔普森
Owner 4DMEDICAL LTD