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Extrusion and granulation production device for granular medicines

A technology of extrusion granulation and production equipment, which is applied in the direction of making medicines into special physical or taking forms, which can solve the problems of insufficient agitation effect and uneven efficacy content of granular medicines, so as to promote moisture Effect of volatilization and improvement of molding efficiency

Inactive Publication Date: 2019-12-13
华润三九(郴州)制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the device can realize extrusion granulation of drug raw materials, in the granulation process, the agitation effect between the raw material components is not sufficient, resulting in an insufficiently uniform drug effect content of the granulated drug obtained by granulation. Therefore, now Provide a granular drug extrusion granulation production device to solve the above technical problems

Method used

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  • Extrusion and granulation production device for granular medicines
  • Extrusion and granulation production device for granular medicines
  • Extrusion and granulation production device for granular medicines

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] see Figure 1-4 , a granular drug extrusion and granulation production device, including a support frame 1, a stirring tank 5 is fixedly installed on the support frame 1, and a turret 8 is connected to the stirring tank 5 through a stirring motor 9, and the turret 8 is equipped with a For the mixing mechanism for agitating and dispersing the drug raw materials, the bottom of the mixing barrel 5 is vertically fixed with an extrusion mechanism, and the bottom of the extrusion mechanism is provided with a cutting mechanism driven by a transmission motor 12. When the extrusion tube 4 is below, there is a The collection tank 2 is provided with a dispersing mechanism inside the collection tank 2.

[0024] The mixing barrel 5 of the device is used to store the raw materials of the medicine, which are stirred and mixed by the mixing mechanism, so that the components of the medicine can be fully mixed, and then the raw materials of the medicine are extruded by the extrusion mech...

Embodiment 2

[0031] In order to facilitate the extrusion of the drug material and the subsequent cutting and granulation, on the basis of Example 1, the extrusion mechanism includes an extrusion tube 4 fixed at the bottom of the mixing barrel 5, and several extrusion tubes are uniformly arranged at the bottom of the extrusion tube 4. Out of the hole 29, the drive shaft 10 extends vertically to the inside of the extruded tube 4, and the surface of the drive shaft 10 is fixed with a helical blade 11.

[0032] The rotation of the drive shaft 10 can drive the spiral blade 11 to rotate and screw the medicinal material inside the mixing barrel 5 into the extruding tube 4. The medicinal material is extruded from the extrusion hole 29 and forms a strip structure. The mechanism then cuts the strip medicine into granules.

[0033] Specifically, the cutting mechanism includes an incomplete gear 21 that is connected to the transmission motor 12 through a pulley mechanism 22. A scraper 24 that slides a...

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Abstract

The invention discloses an extrusion and granulation production device for granular medicines and relates to the technical field of medicine production. The device comprises a support frame, a stirring barrel is fixedly mounted on the support frame, a cutting mechanism driven by a drive motor is arranged at the bottom of an extrusion mechanism, a collecting tank is arranged below an extrusion pipe, and a dispersion mechanism is arranged in the collecting tank. Medicine materials are rotationally stirred and mixed by a mixing mechanism, so that medicine materials of each component can be fullyand uniformly stirred, medicines obtained by extrusion and granulation have full efficacy, the extrusion mechanism can extrude raw materials from an extrusion hole, the cutting mechanism cuts strip-type raw materials extruded from the extrusion hole into granules, an air heater rapidly dries medicines, granular medicines can be rapidly formed, the dispersion mechanism promotes moisture volatilization of medicines, and the forming efficiency is further enhanced.

Description

technical field [0001] The invention relates to the technical field of medicine production, in particular to a granular medicine extrusion granulation production device. Background technique [0002] Pharmaceutical engineering is an engineering major that intersects chemistry, biology, pharmacy and engineering, with the goal of cultivating talents engaged in drug R&D and manufacturing, new technology, new equipment, and new variety development, amplification and design. During the processing and production of granular drugs, it is necessary to granulate the drug raw materials through extrusion granulation equipment to obtain granular drugs. [0003] The patent with the authorized notification number CN208598812U discloses an integrated equipment for granulation and drying of medicines, which includes a granulation chamber on the upper part and a drying chamber on the lower part. The top of the granulation chamber is provided with a feeding port equipped with a feeding valve....

Claims

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Application Information

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IPC IPC(8): A61J3/00
CPCA61J3/00
Inventor 符国成龚小兵陈海刚杨一栋
Owner 华润三九(郴州)制药有限公司
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