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Yarrow fresh-plant pressed juice concentrate, production, and use

A technology of yarrow and plant juice, which is applied in the field of yarrow freshly squeezed plant juice concentrate, and can solve problems such as microbial contamination

Pending Publication Date: 2019-12-13
SYMRISE GMBH & CO KG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The disadvantage is that the freshly squeezed vegetable juice obtained can only be stored well in closed containers, because otherwise there is a risk of microbial contamination

Method used

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  • Yarrow fresh-plant pressed juice concentrate, production, and use
  • Yarrow fresh-plant pressed juice concentrate, production, and use
  • Yarrow fresh-plant pressed juice concentrate, production, and use

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0126] Example 1: Manufacture of freshly squeezed yarrow juice concentrate by freeze drying

[0127] 100 ml of freshly squeezed plant juice of yarrow (Achillea millefolium, Yarrow) made from a flowering herb cultivated in Germany (Schoenenberger) was frozen and subsequently freeze-dried. 5.3 g of dry juice 1a were obtained as a brown-green solid and analyzed for its composition:

[0128] Table 1:

[0129]

[0130] *Quantified as chlorogenic acid

[0131] Three further batches of 100 ml each of freshly squeezed plant juice of yarrow (Achillea millefolium, Yarrow) (Schoenenberger) were frozen and subsequently freeze-dried. The dry juices 1b-1d obtained were weighed and analyzed for the sum of mono- and dicaffeoylquinic acids and rutin:

[0132] Form 2:

[0133]

[0134] *Quantified as chlorogenic acid

[0135] n.d. = not determined

[0136] The results showed that 4 batches of freshly squeezed yarrow (Achillea millefolium, Yarrow) plant juice (Schoenenberger company...

example 2

[0138] Example 2: Manufacture of freshly squeezed yarrow juice concentrate by spray drying

[0139] 1 1 of freshly squeezed yarrow juice (Schoenenberger, dry matter content 5.3%) was mixed with 150 g of maltodextrin DE 17-20 and spray-dried. A beige, free-flowing powder was obtained consisting of 75% maltodextrin and 25% freshly squeezed yarrow juice. Analysis of the sum of mono- and dicaffeoylquinic acids and rutin of the spray-dried concentrate:

[0140] Form 3:

[0141]

[0142] *Quantified as chlorogenic acid

[0143] Analytical results showed that these inclusions remained and did not degrade upon spray drying.

example 3

[0144] Example 3: Effect of freshly squeezed plant juice concentrate of yarrow on gene expression of heat shock proteins in skin cells

[0145] Neonatal human epidermal keratinocytes (nHEK) were incubated with 0.2x 10 6 Density of cells / wells Plates were seeded in microtiter plates with 6 wells and cultured in epidermal cell-specific medium (EpiLife). After an incubation time of 24 hours, the freshly squeezed plant juice concentrate of yarrow in Example 1 was applied at a concentration of 0.005% by weight in a medium specific for epidermal cells and incubated for 24 hours.

[0146] mRNA was isolated and purified with the help of Qiagen's Mini Kit for. The mRNA was eluted from the column with 50 μl of RNase-free water. The purity of the isolated RNA was quantified and determined spectrophotometrically. The purity was assessed via the ratio of absorbance E260 / E280 and E260 / E230. RNA was transcribed into cDNA according to the manufacturer's instructions (RNA-to-cDNA Kit, ...

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Abstract

The invention relates to a yarrow fresh-plant pressed juice concentrate and to a gentle method for producing same. The yarrow fresh-plant pressed juice concentrate is used in cosmetic compositions, pharmaceutical compositions, food compositions, or dietary supplements. The present invention additionally relates to new aspects of the use of yarrow. According to the invention, the use of yarrow stimulates the expression of heat shock proteins and / or antimicrobial peptides in skin cells. The invention further relates to the use of yarrow to increase the thermal tolerance of the skin.

Description

technical field [0001] The present invention relates to a freshly squeezed yarrow juice concentrate which can be stored for a long period of time without using heat treatment, preservatives or other additives. Furthermore, the present invention relates to a gentle process for the manufacture of this yarrow freshly squeezed plant juice concentrate. The freshly squeezed plant juice concentrate of yarrow is used in a cosmetic composition, a pharmaceutical composition, a food composition or a dietary supplement. [0002] The present invention also relates to a new viewpoint on the use of yarrow. The present invention provides a use of yarrow for stimulating the expression of heat shock proteins and / or antimicrobial peptides in skin cells. Furthermore, a use of yarrow for improving the heat resistance of the skin is described. Background technique [0003] Yarrow (Achillea millefollium, Yarrow) is a traditional medicinal plant. Typical inclusions include, for example: essenti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61K36/28A61K9/00A61K47/10A61K47/36A61K9/107A61Q5/00A61Q11/00A61Q19/00
CPCA61Q5/00A61Q11/00A61Q19/00A61K8/97A61K9/0014A61K47/10A61K47/36A61K9/107A61K36/28A61K2236/00A61P17/00A23L2/08A23L2/52A23L2/085A23L2/102A23L2/12A61K8/9789A23L2/04
Inventor 马丁纳·赫尔曼桑德拉·盖布勒曼努埃尔·佩萨罗多米尼克·斯图尔曼莉萨·加布茱莉亚·迈耶
Owner SYMRISE GMBH & CO KG
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