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Breast tumor localization analysis method based on dynamic enhanced magnetic resonance imaging

A magnetic resonance imaging and breast tumor technology, applied in the field of tumor detection, can solve the problems of observer variability, increased misdiagnosis and missed diagnosis of breast lesions, and achieve the effect of reducing workload, improving diagnostic efficiency and reducing missed diagnosis

Active Publication Date: 2022-03-08
SICHUAN UNIV
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Problems solved by technology

[0005] Automated assessment at specialized workstations helps interpret contrast-enhancing patterns in MRI volumes, but humans are still required to identify and characterize suspicious areas, increasing the risk of misdiagnosing and missing breast lesions and potentially leading to intra-observer variability

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  • Breast tumor localization analysis method based on dynamic enhanced magnetic resonance imaging
  • Breast tumor localization analysis method based on dynamic enhanced magnetic resonance imaging
  • Breast tumor localization analysis method based on dynamic enhanced magnetic resonance imaging

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Embodiment Construction

[0047] The technical solution of the present invention is described in conjunction with the embodiments.

[0048]The processing algorithm of the present invention firstly corrects the motion artifact and segments the breast; secondly, combines the speckle and relative enhanced voxel features to perform preliminary positioning on the breast region. Then, by combining the morphological and dynamic features of the candidate areas, the benign and malignant detection classification of the lesion area is performed, and low false positives are ensured. Finally, the performance of the algorithm is evaluated using free response operating characteristic analysis (FROC), which has high sensitivity in detecting malignant lesions with an acceptable number of false positives. The data showed that if 0.1, 1, 4 or 7 false positive results were allowed per normal sample, the sensitivities were 0.71, 0.83, 0.90 and 0.95, respectively.

[0049] specific:

[0050] (1) Motion Correction

[0051...

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Abstract

The present invention provides a breast tumor localization analysis method based on dynamic enhanced magnetic resonance imaging, comprising the following steps: firstly, correcting motion artifacts and segmenting the breast; secondly, performing preliminary localization on the mammary gland region by combining speckle and relative enhancement voxel features; and then , by combining the morphological and dynamic features of the candidate regions, classify benign and malignant lesion regions, and ensure low false positives; finally, use the free response operation characteristic analysis to evaluate the performance of the algorithm. The breast tumor localization analysis method based on dynamic enhanced magnetic resonance imaging provided by the present invention can realize relatively rapid lesion localization and benign and malignant analysis based on computer-aided diagnosis of mammary tumors. When a single false positive is allowed in each case, The detection sensitivity of malignant lesions was 83%. Provide convenience for doctors, reduce workload, reduce missed diagnosis and misdiagnosis rate, and improve diagnosis efficiency.

Description

technical field [0001] The invention belongs to the technical field of tumor detection, and in particular relates to a breast tumor location analysis method based on dynamic enhanced magnetic resonance imaging. Background technique [0002] Breast disease is one of the most common diseases affecting women all over the world. The incidence of breast cancer is about 10% to 15%, and it is the cancer with the highest incidence rate among Chinese women. Early detection and treatment can significantly improve breast cancer disease survival. Among population-based breast screening, the most widely used is mammography. However, for high-risk patients, screening with dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is usually recommended. DCE-MRI is highly sensitive, especially for younger patients with dense breasts. In addition, DCE-MRI scanning technology can provide various information such as hemodynamics and morphology of breast lesions, which is helpful for th...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06T7/00G06T7/11G06T7/62G06T7/73
CPCG06T7/0012G06T7/11G06T7/62G06T7/73G06T2207/10096G06T2207/30068G06T2207/30096
Inventor 刘奇崔婧轩
Owner SICHUAN UNIV
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