A kind of herbal oral antibacterial spray containing propolis and preparation method thereof

A technology of herbal oral cavity and propolis, which is applied in the direction of medical preparations containing active ingredients, oral care, local antibacterial agents, etc., can solve the problems of not being able to realize the maximum utilization of beneficial ingredients most effectively, so as to increase the body's immunity and taste good , the effect of promoting tissue regeneration

Active Publication Date: 2022-05-24
北京中蜜科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the beneficial ingredients in propolis are often heat-sensitive or easily decomposed substances, and directly adding propolis cannot achieve the maximum utilization of the beneficial ingredients most effectively

Method used

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  • A kind of herbal oral antibacterial spray containing propolis and preparation method thereof
  • A kind of herbal oral antibacterial spray containing propolis and preparation method thereof
  • A kind of herbal oral antibacterial spray containing propolis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] A herbal oral antibacterial spray containing propolis is prepared from the following raw materials by weight:

[0051] 0.1 part of propolis extract, 5 parts of grass coral extract, 2 parts of licorice extract, 2 parts of honeysuckle extract, 3 parts of fat sea extract, 0.5 part of borneol, 1 part of menthol, 0.05 part of chlorhexidine acetate, xylose 0.3 parts of alcohol, 0.1 part of food essence, 30 parts of ethanol and purified water make up 100 parts of the total amount.

[0052] Wherein said propolis extract is prepared by the following method:

[0053] 1) Firstly, pre-treat the propolis by cleaning and removing impurities, then add the pre-treated propolis into an extractor equipped with an ultrasonic generator, add ethanol solution and petroleum ether with a concentration of 95% by mass, and stir at 40°C Extract for 30 minutes, filter after cooling, repeat 3 times to combine the extracts, concentrate under reduced pressure to obtain propolis extract, wherein the ...

Embodiment 2

[0070] A herbal oral antibacterial spray containing propolis is prepared from the following raw materials by weight:

[0071] 0.1 part of propolis extract, 5 parts of grass coral extract, 3 parts of licorice extract, 8 parts of honeysuckle extract, 2 parts of fat sea extract, 0.5 part of borneol, 1 part of menthol, 0.05 part of chlorhexidine acetate, xylose 0.3 parts of alcohol, 0.1 part of food essence, 30 parts of ethanol and purified water make up 100 parts of the total amount.

[0072] Refer to Example 1 for the preparation method of the propolis extract, grass coral extract, licorice extract, honeysuckle extract, fat sea extract, and the propolis-containing herbal oral antibacterial spray.

Embodiment 3

[0074] A herbal oral antibacterial spray containing propolis is prepared from the following raw materials by weight:

[0075] 0.2 parts of propolis extract, 4 parts of grass coral extract, 3 parts of licorice extract, 6 parts of honeysuckle extract, 3 parts of fat sea extract, 0.5 part of borneol, 1 part of menthol, 0.05 part of chlorhexidine acetate, xylose 0.5 part of alcohol, 0.01 part of food essence, 25 parts of ethanol and purified water make up 100 parts of the total amount.

[0076] Refer to Example 1 for the preparation method of the propolis extract, grass coral extract, licorice extract, honeysuckle extract, fat sea extract, and the propolis-containing herbal oral antibacterial spray.

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PUM

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Abstract

The invention discloses a propolis-containing herbal oral antibacterial spray, which is composed of the following raw materials in parts by weight: 0.1-10 parts of propolis extract, 5-30 parts of grass coral extract, 1-20 parts of licorice extract, and honeysuckle 1‑20 parts of extract, 1‑10 parts of fat sea extract, 0.5‑10 parts of borneol, 0.1‑10 parts of menthol, 0.02‑5 parts of chlorhexidine acetate, 0.1‑2 parts of xylitol, 0.05 parts of food flavor 0.2 parts, 15‑30 parts of ethanol and purified water make up the total amount of 100 parts. According to the present invention, the propolis-containing herbal oral antibacterial spray has good taste, long shelf life, antibacterial, anti-inflammatory, heat-clearing and detoxifying effects. The formula is mainly based on herbal plant active ingredients and propolis, and a small amount of chemical drug chlorhexidine acetate is added. The synergistic effect between the various raw materials can not only expand the antibacterial spectrum of the product, improve the antibacterial effect of the product, but also reduce the antibacterial effect of the product. Irritation to the skin, to ensure the safety of the product.

Description

technical field [0001] The invention relates to the field of antibacterial sprays belonging to oral care products, in particular to a herbal oral antibacterial spray containing propolis and a preparation method thereof. Background technique [0002] There are a lot of bacteria in the mouth, especially after going to bed at night, the mouth is closed, the air is not circulated, and there is a lot of secretions. Therefore, after a night, many bacteria grow and the mouth is prone to odor. In addition, patients with dental caries, gingivitis, periodontitis, oral mucositis, tooth decay, periodontal disease and other oral diseases are more likely to breed bacteria in their mouths, especially anaerobic bacteria, which decompose and produce sulfides, which emit putrefaction. taste, resulting in bad breath. Therefore, maintaining oral hygiene and inhibiting the growth of oral bacteria has a positive effect on personal care. [0003] At present, the common oral antibacterial sprays ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/04A61K8/98A61K8/9789A61K8/34A61K8/43A61Q11/00A61Q17/00A61P1/02A61P31/02
CPCA61K8/046A61K8/988A61K8/9789A61K8/34A61K8/43A61K8/345A61Q11/00A61Q17/005A61P1/02A61P31/02A61K2800/592A61K2800/5922A61K2800/805A61K2800/82
Inventor 张杨张加东冯浩然曹珍艳国占宝王秀红
Owner 北京中蜜科技发展有限公司
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