Propolis-containing herbaceous oral cavity bacteriostasis spray agent and preparation method thereof

A technology of herbal oral cavity and propolis, which is applied in the direction of medical preparations containing active ingredients, oral care, local antibacterial agents, etc., can solve the problems of not being able to realize the maximum utilization of beneficial ingredients most effectively, and achieve the purpose of increasing the body's immunity and long shelf life , reducing the stimulating effect

Active Publication Date: 2020-01-24
北京中蜜科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the beneficial ingredients in propolis are often heat-sensitive or easily decomposed substances, and directly adding propolis cannot achieve the maximum utilization of the beneficial ingredients most effectively

Method used

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  • Propolis-containing herbaceous oral cavity bacteriostasis spray agent and preparation method thereof
  • Propolis-containing herbaceous oral cavity bacteriostasis spray agent and preparation method thereof
  • Propolis-containing herbaceous oral cavity bacteriostasis spray agent and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] A herbal oral antibacterial spray containing propolis is prepared from the following raw materials by weight:

[0051] 0.1 part of propolis extract, 5 parts of grass coral extract, 2 parts of licorice extract, 2 parts of honeysuckle extract, 3 parts of fat sea extract, 0.5 part of borneol, 1 part of menthol, 0.05 part of chlorhexidine acetate, xylose 0.3 parts of alcohol, 0.1 part of food essence, 30 parts of ethanol and purified water make up 100 parts of the total amount.

[0052] Wherein said propolis extract is prepared by the following method:

[0053] 1) Firstly, pre-treat the propolis by cleaning and removing impurities, then add the pre-treated propolis into an extractor equipped with an ultrasonic generator, add ethanol solution and petroleum ether with a concentration of 95% by mass, and stir at 40°C Extract for 30 minutes, filter after cooling, repeat 3 times to combine the extracts, concentrate under reduced pressure to obtain propolis extract, wherein the ...

Embodiment 2

[0070] A herbal oral antibacterial spray containing propolis is prepared from the following raw materials by weight:

[0071] 0.1 part of propolis extract, 5 parts of grass coral extract, 3 parts of licorice extract, 8 parts of honeysuckle extract, 2 parts of fat sea extract, 0.5 part of borneol, 1 part of menthol, 0.05 part of chlorhexidine acetate, xylose 0.3 parts of alcohol, 0.1 part of food essence, 30 parts of ethanol and purified water make up 100 parts of the total amount.

[0072] Refer to Example 1 for the preparation method of the propolis extract, grass coral extract, licorice extract, honeysuckle extract, fat sea extract, and the propolis-containing herbal oral antibacterial spray.

Embodiment 3

[0074] A herbal oral antibacterial spray containing propolis is prepared from the following raw materials by weight:

[0075] 0.2 parts of propolis extract, 4 parts of grass coral extract, 3 parts of licorice extract, 6 parts of honeysuckle extract, 3 parts of fat sea extract, 0.5 part of borneol, 1 part of menthol, 0.05 part of chlorhexidine acetate, xylose 0.5 part of alcohol, 0.01 part of food essence, 25 parts of ethanol and purified water make up 100 parts of the total amount.

[0076] Refer to Example 1 for the preparation method of the propolis extract, grass coral extract, licorice extract, honeysuckle extract, fat sea extract, and the propolis-containing herbal oral antibacterial spray.

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Abstract

The invention discloses a propolis-containing herbaceous oral cavity bacteriostasis spray agent. The propolis-containing herbaceous oral cavity bacteriostasis spray agent consists of the following rawmaterials in parts by weight of 0.1-10 parts of a propolis extract, 5-30 parts of a sarcandra glabra extraction solution, 1-20 parts of a licorice root extraction solution, 1-20 parts of a honeysuckle flower extraction solution, 1-10 parts of a semen sterculiae lychnophorae extraction solution, 0.5-10 parts of borneol, 0.1-10 parts of menthol, 0.02-5 parts of chlorhexidine acetate, 0.1-2 parts ofxylitol, 0.05-0.2 part of edible essence, 15-30 parts of ethanol and the balance purified water, wherein the total parts by weight of the raw materials are 100. The propolis-containing herbaceous oral cavity bacteriostasis spray agent disclosed by the invention is good in mouth feel and long in quality guarantee period, and has the effects of resisting bacteria, diminishing inflammation, clearingheat and removing toxicity. Herbaceous plant active components and the propolis are used as main components of the formula of the propolis-containing herbaceous oral cavity bacteriostasis spray agent, a small quantity of a chemical medicine namely the chlorhexidine acetate is added, and all the raw materials are in synergistic effects, so that the bacteriostasis spectrum of the product can be enlarged, the bacteriostasis effect of the product is promoted, irritants of the product to skin can be reduced, and the safety of the product can be guaranteed.

Description

technical field [0001] The invention relates to the field of antibacterial sprays belonging to oral care products, in particular to a herbal oral antibacterial spray containing propolis and a preparation method thereof. Background technique [0002] There are a lot of bacteria in the mouth, especially after going to bed at night, the mouth is closed, the air is not circulated, and there is a lot of secretions. Therefore, after a night, many bacteria grow and the mouth is prone to odor. In addition, patients with dental caries, gingivitis, periodontitis, oral mucositis, tooth decay, periodontal disease and other oral diseases are more likely to breed bacteria in their mouths, especially anaerobic bacteria, which decompose and produce sulfides, which emit putrefaction. taste, resulting in bad breath. Therefore, maintaining oral hygiene and inhibiting the growth of oral bacteria has a positive effect on personal care. [0003] At present, the common oral antibacterial sprays ...

Claims

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Application Information

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IPC IPC(8): A61K8/04A61K8/98A61K8/9789A61K8/34A61K8/43A61Q11/00A61Q17/00A61P1/02A61P31/02
CPCA61K8/046A61K8/988A61K8/9789A61K8/34A61K8/43A61K8/345A61Q11/00A61Q17/005A61P1/02A61P31/02A61K2800/592A61K2800/5922A61K2800/805A61K2800/82
Inventor 张杨张加东冯浩然曹珍艳国占宝王秀红
Owner 北京中蜜科技发展有限公司
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