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Lacrimal fluid layer evaluation method, computer program, and device

An evaluation method, tear technology, applied in computing, medical science, image data processing, etc., can solve problems such as inability to evaluate correctly, and achieve the effect of reducing the load on the device

Pending Publication Date: 2020-02-21
KOWA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0017] In addition, both the devices of Patent Document 1 and Patent Document 2 have the problem that if a reflected light image or a reflected light amount with a sharpness and brightness above a predetermined level cannot be obtained, accurate evaluation may not be possible, so position matching is required. fine-tuning, and the threshold needs to be adjusted according to the state and surrounding environment of each subject

Method used

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  • Lacrimal fluid layer evaluation method, computer program, and device
  • Lacrimal fluid layer evaluation method, computer program, and device
  • Lacrimal fluid layer evaluation method, computer program, and device

Examples

Experimental program
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Embodiment 1

[0039]

[0040] As for the device for acquiring the interference fringe image of the tear layer on the surface of the cornea (tear layer interference fringe image acquisition device), conventionally known devices can be suitably used as long as the captured image can be recorded as digital data. For example, there is a tear layer interference fringe image acquisition device, such as Figure 4 As shown in the outline, the light emitted from the light source 11 and passed through the diaphragm (Japanese: twist り) sequentially passes through the lens 12, the beam splitter (Japanese: splitta) 13, and the objective lens 14, and then condenses the light onto the subject's eye. The anterior eye 15. The reflected light from the anterior segment 15 passes through the objective lens 14 and the beam splitter 13 , and passes through the imaging lens 16 to be imaged on the imaging element 17 . The imaging data imaged on the imaging element 17 is subjected to predetermined processing by ...

Embodiment 2

[0082] In Embodiment 1, when judging tear collapse, it is judged based on a value indicating color deviation as a judgment value calculated from color information, but the judgment value may be judged as follows for tear collapse instead of A value representing the bias of this color.

[0083] The position where the tear layer collapses has a characteristic that generally the whiteness is strong and shows a value larger than that of a position where the luminance does not collapse. Therefore, the average brightness of the pixels in the local region of the extracted image is calculated, and the pixels in the local region that show brightness equal to or higher than the average brightness value are extracted.

[0084] The number of extracted pixels is counted, and when the counted number is equal to or greater than a predetermined threshold, it is determined that the tear layer has collapsed. In addition, tear layer collapse may be determined when not the number of pixels, but ...

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Abstract

Provided are a lacrimal fluid layer evaluation method, a computer program and a device which are non-invasive and objective, reduce the load as compared to measuring BUT, and meet new standards for dry eye diagnosis. This method includes: a step for detecting, as the eyelid opening time, when there is a change beyond a threshold value in color information within a prescribed region of a lacrimal fluid interference fringe image; a step for extracting, from the lacrimal fluid interference fringe image, as an extraction image, an image corresponding to the time when a prescribed amount of time has elapsed from the eyelid opening time; a determination value calculation step for scanning a prescribed subject region of the extraction image, and calculating a determination value from color information of a pixel of a local region; a step for comparing the calculated determination value and the threshold value to detect a relevant pixel; and an evaluation step for comparing the detected pixeland the threshold value to evaluate whether lacrimal fluid layer destruction is indicated.

Description

technical field [0001] The present invention relates to a method, a computer program, and a device for non-invasively evaluating the state and collapse of the tear layer to determine whether it is dry eye. Background technique [0002] Eyeballs and eyelids are protected by tears to prevent the invasion of foreign matter, dryness, and damage caused by friction. The tear layer is made up of two layers, a liquid layer made up of water and glycoproteins (mucins) that make up more than half of it, and an oil layer covering it; the oil layer prevents the liquid layer from coming into contact with the air directly. of evaporation. A component of the oily layer is secreted from the meibomian glands present in the eyelids. If the meibomian glands are damaged due to aging, inflammation, and abrasions, etc., a normal oil layer cannot be formed to maintain a liquid layer, etc., thus causing a symptom called dry eye. [0003] Conventionally, "lacrimal gland secretion test" and "BUT (B...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B3/10
CPCA61B3/101G06T7/0012G06T2207/10024G06T2207/30041G06T2207/20021A61B3/14
Inventor 薮崎克己
Owner KOWA CO LTD