Optical analysis device for long-strip-shaped fluorescence signal detection

Abstract

The invention discloses an optical analysis device for long-strip-shaped fluorescence signal detection, and solves the technical problems of low sensitivity, poor repeatability and large background signal interference in traditional light path detection of long-strip-shaped fluorescence signals. The device comprises a detection circuit, an optical analysis device housing, an excitation light source which is packaged in the optical analysis device shell and used for emitting excitation light, and an optical assembly which is located in the illumination direction of the excitation light source and used for accurately projecting the excitation light to a detection line T of a detected object, converging fluorescence emitted by the detection line T and then projecting the fluorescence to the detection circuit. The device is simple in structure, scientific and reasonable in design and convenient to use. By improving the exciting light utilization rate, increasing the receiving amount of a receiving light path and controlling the shape of an exciting light spot, the background signal interference is reduced, and therefore the detection sensitivity and repeatability are improved.

Description

technical field [0001] The invention relates to an optical analysis device for detecting strip fluorescent signals. Background technique [0002] Fluorescence immunoassay analyzer is an instrument that uses rare earth markers for ultra-trace analysis. The basic principle is to mark the antibody with rare earth elements to make a reagent, and irradiate it with a light source of a specific wavelength as the excitation light, and the reagent will be excited to emit another wavelength of fluorescence, and the diagnosis can be made by optically analyzing the fluorescence . [0003] Among them, the optical analysis device is a key component of the fluorescence immunoassay analyzer. The optical analysis device of the existing fluorescence immunoassay analyzer usually gathers the emitted light of the divergent point light source through a convex lens and irradiates it on the object to be tested to form a circular shape. small spot. However, for fluorescent immunochromatography te...

AI Technical Summary

Problems solved by technology

However, for fluorescent immunochromatography test strips and long fluorescent signals formed by our company's microfluidic chip, using this traditional optical path for detection, if the spot is small, the spot cannot cover the entire fluorescent signal area, resulting in fluorescence The signal is weak and the fluorescence utilization rate is not high; if the spot is large, it will cover too much background signal area while cove

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