The invention relates to a laser welding device, particularly to a laser welding device carrying multiple sensors. The device comprises a laser 1, a convex lens 2, a coaxial optical sensor 3, a lateral optical sensor 4, an acoustic sensor 5, a back sensor 6, a welding pool 7, a welded material 8, a charge detection meter 9, a welding nozzle 10, inert shielding gas 11 and a half-reflecting mirror 12, wherein the back sensor 6 is mounted at the back of the welded material 8; the welded material 8 is in series connection with the welding nozzle 10 through a lead; the middle of the lead is also in series connection with the charge detection meter 9. With the adoption of the device, refractory materials such as titanium, quartz and the like can be welded, anisotropic materials can be welded, and the effect is good; the device is exquisite in structure as well as safe and reliable to use and has the certain economical and applicable value, and the equipment manufacturing cost is moderate; the welding quality is good, the automation degree is high, and a large quantity of manpower and material resources are saved.