The invention discloses a monazite 10-micron small-beam-spot LA-Q-ICP-MS U-Th-Pb age determination method. The method includes the steps that a standard solution sample with the concentration of 1 ppb is directly led into a four-level-rod inductively coupled plasma mass spectrometer, the instrument parameters are optimized, the response strength of <205>T1 is larger than 200,000 cps/ppb, the relative standard deviation is 1% to 2%, the double charges are smaller than 1.5%, and the yield of oxidation is smaller than 1%; an artificial glass NTSI 610 solid standard sample is led into the four-level-rod inductively coupled plasma mass spectrometer in a laser ablation mode, carrier gas of a laser and carrier gas of the four-level-rod inductively coupled plasma mass spectrometer are matched, and counting of <238>U reaches the maximum; a monazite standard sample 44069 is led into the four-level-rod inductively coupled plasma mass spectrometer in a laser ablation mode, the density of laser energy is 3 J/cm<2>, the impulse frequency is 4 Hz, and the age of monazite U-Th-Pb is determined through a 10-micron small laser beam spot. By means of the method, the space resolution ratio of monazite LA-Q-ICP-MS U-Th-Pb age determination is increased, and the testing requirement of monazite is met.