The invention discloses a rib-pillar-free continuous sublevel filling method for mining preparation in a medium-thickness slope crushed ore body vein. The method comprises the following steps of: dividing a mine block into panel structures with a plurality of sections and bunches, namely dividing sections in a panel, not leaving a rib pillar in the sections, and dividing continuous extraction units; arranging a slope ramp of the panel on an ore body hanging wall, and arranging sectional roadways namely rock drilling ore removal gate ways in the vein; making all the sectional roadways in the panel mutually communicated, and the allocation and transportation of trackless equipment flexible and convenient; performing quarry central up cutting before the extraction, and ensuring the deep hole construction in a quarry upward sector in good conditions; performing operation such as multiple-section quarry rock drilling, blasting, supporting, ore removing, filling and paralleling; using a rib-pillar-free continuous extraction way backing from two wings of the panel to the center in the same sectional quarry, wherein an extraction process is performed sequentially; and filling a gob with tailings or waste stones. The invention relates to the rib-pillar-free continuous sublevel filling method suitable for medium-thickness slope crushed ore bodies, which has a low mining preparation ratio, low loss and high efficiency and the extraction is safe.