This invention relates to experimental systems and methods for research on
photodynamic therapy,
photothermal therapy, and their combinations. The
experimental system includes: an optical
irradiation module comprising multiple
laser sources, each capable of outputting a collimated beam, which is then combined to form a coaxial
optical path and projected onto the surface of the observed object via a beam adjustment component; an
optical path position adjustment module including an electric Z-axis displacement mechanism; a
temperature monitoring module including an active
temperature control substrate, an
infrared thermal imager, and a
fiber optic temperature probe interface; and a
data acquisition and control module configured to: synchronously acquire
laser output power, spot area, electric Z-axis position, temperature of the active
temperature control substrate, temperature sequences of multiple different regions, and
fiber optic temperature probe data, and
record the above data with a unified
timestamp; calculate
power density based on the real-time output power and spot area of the
laser sources; and automatically control the
laser source to shut off its output when the data from any
temperature monitoring channel exceeds a preset safety threshold.