Low trauma wound dressing with improved moisture vapor permeability
A wound dressing and permeability technology, applied in the field of wound dressings, can solve the problems of lack of initial skin adhesion and peeling off.
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Embodiment 1
[0167] Synthesis of microspheres
[0168] (Adhesive No. 1-19)
[0169] (1) 450 g of deionized water, (2) 6 grams of Standapol® A (an ammonium lauryl sulfate emulsifier available from Henkel AG), (3) 0.72 grams of Lucidol®-70 (a type of ammonium lauryl sulfate available from Henkel AG) Pennwalt Corporation's benzoyl peroxide), and (4) a mixture of 150 grams of monomers of isooctyl acrylate, isodecyl acrylate, acrylic acid, N-vinylpyrrolidone, and poly(ethylene oxide) acrylate was charged to the attached In a one-liter resin reactor with a mechanical stirrer, a condenser, and inlet and outlet pipes, the monomer ratios are shown in Table 2 and Table 4. Prior to polymerization into Adhesives 15 and 16, the monomer suspension was homogenized in an Omni(R) mixer (available from Omni International Inc.). Then, the mixture was stirred at 400 rpm to polymerize the residue. Vacuumize the gas in the reaction vessel, and replace the reaction vessel with argon until the polymerization i...
Embodiment 2
[0171] Adhesive Test (Adhesive No. 1-19)
[0172] Measure the initial water vapor transmission rate (vertical) MVTR of the sample according to the determination method described here up , initial skin adhesion (T 0 ) and skin adhesion after 24 hours of continuous contact with the skin (T 24 ), and the test results are shown in Table 3.
[0173] adhesive #
[0174] sample #
Embodiment 3
[0176] Synthesis of Microspheres (Adhesive No. 20-40)
[0177] Add (i) 450 grams of deionized water, (ii) 6 grams of Standapol® A (dodecyl alcohol purchased from Henkel A G) to a 1-liter resin reactor equipped with a mechanical stirrer, condenser, and inlet-outlet piping. Ammonium sulfate emulsifier, (iii) 0.72 grams of Lucidol-70 (benzoyl peroxide from Pennwalt Corporation) and (iv) 150 grams of monomeric isooctyl acrylate, N-vinylpyrrolidone, acrylic acid and poly(epoxy ethane) acrylate mixture, mixed according to the monomer ratios listed in Table 2 and Table 4. For adhesives 20, 23-26 and 32-36, before polymerization, the monomer suspension was mixed in an Omni mixer (purchased from Omni International Inc.). For the polymerization of the residue, the mixture was stirred at 400rpm. The gas in the reaction vessel was evacuated and replaced with argon until the polymerization was completed. The temperature of the reactor rose to 55- 65°C, in order to complete the polymeriz...
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Abstract
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