Collection device and collection method for internal jugular vein indwelling blood sample of tree shrew

Abstract

The invention discloses a collection device and a collection method for an internal jugular vein indwelling blood sample of a tree shrew, and mainly relates to the technical field of tree shrew experimental blood collection. The collection device comprises a puncture needle, an indwelling blood sampling hose and an indwelling box, wherein the puncture needle comprises a detachable part and a needle handle; the detachable part comprises two detachable needle body parts and two detachable needle body fixing shells; and the indwelling box comprises a seat body, a tube body pressing and holding fixed rubber plug, a clamping seat, a sealing plug and a protective cap. The collection method is a use method of the blood sample collection device. The collection device and the collection method provided by the invention have the following beneficial effects: the collection device can be used for a plurality of times of blood collection through one-time blood vessel puncture, is applicable to continuous blood collection or time-phased indwelling blood collection, and is good in fixing effect and not prone to falling off; the movement of the neck of the tree shrew cannot influence the indwelling blood collection tube indwelled in the jugular vein; and the indwelling blood collection tube indwelled in the jugular vein cannot damage the vein wall. Meanwhile, the indwelling blood sampling device can also be used for medicine administration.

Description

technical field [0001] The invention relates to the technical field of tree shrew experimental blood collection, in particular to a blood sample collection device and a collection method for tree shrews indwelling in the internal jugular vein. Background technique [0002] The tree shrew is a small climbing mammal. The tree shrew whole genome sequencing analysis and a number of research results at home and abroad show that its kinship is the closest (about 93.4%) to primates, and is closer to humans in anatomy and physiology than commonly used rodent experimental animals such as mice and rats , and can suffer from many diseases similar to humans, and has unique application advantages in the study of animal models of human diseases, mainly used in the research of tumors, nerves, endocrine, immunity and viruses, bacteria, parasites and other fields. In research, it is often necessary to collect blood and administer medicines to tree shrews multiple times. Because the interna...

AI Technical Summary

Problems solved by technology

However, there are many shortcomings and inconveniences in this method

[0004] During the experiment, it is usually necessary to collect blood or give medicines to the tree shrew several times within a certain period of time, as shown in the accompanying drawing Image 6 The position of the internal jugular vein is shown. Since the internal jugular vein of the tree shrew is only about 3mm, the protrusion of the internal jugular vein is not obvious during the actual operation, and the puncture has a certain risk of failure. At the same time, the neck of the tree shrew will stretch and move during the operation. Blood vessels are easily punctured by needles, causing excessive damage to tree shrew blood vessels, and multiple punctures in a short period of time also increase the risk of blood infection, which affects the experimental results

For the operator, every time blood collection needs to puncture the blood vessel of the tree shrew, the operation is cumbersome and wastes valuable scientific research time

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