A mold and method for preparing multi-channel nerve guide

Abstract

The invention provides a mold for preparing a multi-channel nerve guide, comprising a hollow tubular body; a first end cap is installed on one end of the tubular body, the first end cap comprises a first cap body, and the first cap body has a The first blocking part protruding inside the body; the other end of the tube body is equipped with a second end cap, the second end cap includes a second cap body and a multi-needle cap, the second cap body is provided with a liquid injection port, and when the liquid injection The mouth has a second blocking portion protruding toward the inside of the tube body; the multi-needle cap is installed on the liquid injection port and has several channel needles extending along the axis of the tube body. The multi-channel nerve conduit mold provided by this application is simple in design and easy to assemble. The length of the edge is easy to suture the epineurium, avoiding the exposure of the broken end, destroying the internal environment of nerve repair and inflammatory reactions. The tube body can be split into two halves. Easy to take out, the fixed multi-needle cap can take out all the inserted needles at one time, the channel is thin, and avoids damage to the surrounding channels by multiple taking out operations.

Description

technical field [0001] The invention relates to the technical field of medical devices, in particular to a mold and method for preparing a multi-channel nerve guide. Background technique [0002] Peripheral nerve defect is a common clinical symptom. When the distance of nerve defect is long and the tension-free nerve end-to-end anastomosis cannot be achieved through measures such as free nerve, nerve transplantation is usually required. However, allogeneic nerve transplantation faces the problem of immune rejection, and autologous nerve transplantation has disadvantages such as limited sources and permanent denervation dysfunction in the donor site. Therefore, the development of tissue engineered nerves as a substitute for nerve transplantation has become an important research for nerve defect repair. field. [0003] The three elements of tissue engineering are scaffold, seed cells and factors. The biomaterial scaffolds for constructing tissue-engineered nerves can be coll...

AI Technical Summary

Problems solved by technology

[0008] In addition, the currently provided methods for preparing multi-channel nerve conduits are complex and time-consuming. The second freeze-drying involves the rewetting of the first freeze-dried sample, which will inevitably destroy the original structure. The compound of the double-layer structure is easy to delaminate during use. disengagement problem

In addition, the use of various chemical reagents and cross-linking agents will inevitably have chemical residue problems, and the removal by soaking will also destroy the structure of the finished product, and the final product will be unstable.

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