Cartilage defect repair module and method for forming same

A cartilage repair and cartilage technology, which is applied in the medical field to achieve the effects of weight-bearing, reliable effect and making up for insufficient sources

Active Publication Date: 2020-06-16
PEKING UNIV FIRST HOSPITAL
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the stability of the cell state and the sustainability of the scaffold are still a big problem.

Method used

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  • Cartilage defect repair module and method for forming same
  • Cartilage defect repair module and method for forming same
  • Cartilage defect repair module and method for forming same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0040] Such as Figure 5 Shown is a flowchart of a method for forming a module for repairing a cartilage defect provided by the present invention. As can be seen from the figure, the method includes:

[0041] Obtain the mechanical parameters of normal cartilage;

[0042] Establishing a virtual model of the module for cartilage repair according to the mechanical parameters of normal cartilage;

[0043] Using the 3D printing method and the virtual model, a repairing module matching the cartilage defect to be repaired is formed.

[0044] Wherein, the mechanical parameters of normal cartilage include strength and elastic modulus of normal cartilage. The above-mentioned parameters of normal cartilage are the average normal parameters of human cartilage tissue, and are obtained based on the measurement of a large number of normal cartilages that need surgery for various reasons. According to the mechanical parameters of normal cartilage, establishing a virtual model of the module...

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Abstract

The invention discloses a cartilage defect repairing module and a forming method thereof. The forming method comprises the steps: obtaining mechanical parameters of normal cartilage; establishing a virtual model of a cartilage repair module according to the mechanical parameters of the normal cartilage; and forming a repairing module matched with the cartilage defect to be repaired by using a 3D printing method and the virtual model. The cartilage defect repair module formed by the method can be applied to the cartilage defect of a patient, can replace the cartilage of the patient, can achievethe effects of load bearing and intra-articular friction, can overcome the defect that cartilage repair grafts are insufficient in source, and is simple and convenient to transplant in an operation and reliable in effect.

Description

technical field [0001] The invention relates to the field of medical technology, in particular to a module for repairing cartilage defects and a forming method thereof. Background technique [0002] Articular cartilage degeneration is a physiological process that human science has been unable to fully explain and change. Severe osteoarthritis caused by degeneration of articular cartilage brings great pain to patients. At present, the clinical treatment methods for articular cartilage degeneration mainly include arthroscopic subchondral bone microfracture, cartilage transplantation and artificial joint replacement surgery. Cartilage damage is the main cause of articular cartilage degeneration. Small area (less than 5mm 2 ) cartilage defect mainly adopts arthroscopic subchondral bone microfracture technology (drilling to cancellous bone), and uses the repair ability of bone marrow stem cells to repair. For larger areas (5mm 2 -2cm 2 ) for cartilage defects, the mosaic te...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/28A61F2/30
CPCA61F2/28A61F2/30756A61F2/30942A61F2002/2835A61F2002/30759A61F2002/30985A61F2002/30329
Inventor 杨昕闫婕曹永平李淳德
Owner PEKING UNIV FIRST HOSPITAL
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