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Hyaline cartilage, Fibrocartilage and Elastic cartilage are the three major types of cartilage in the human body. A cartilage is made up of extracellular matrix composed of collagen fibers, ground substance that is rich in proteoglycan, and elastin fibers. The three types of cartilage, described above,...
Method for low-density expansion of human cartilage cells
It is an object of the present invention a method to obtain a cartilage cell population enriched in cartilage progenitor cells (CPCs), said method comprising culturing said cells in culture at a density between 10 and 500 cells / cm2. In a further aspect, it is here claimed a population of cartilage cells enriched in CPCs obtainable by means of said method, and their use in the treatment of chondral lesions or joint degeneration.
Owner:OSPEDALE GALEAZZI SPA